Updated analysis of the surface carbohydrate gene clusters in a diverse panel of Acinetobacter baumannii isolates

JJ Kenyon, RM Hall - Antimicrobial Agents and Chemotherapy, 2022 - Am Soc Microbiol
To enhance the utility of the genetically diverse panel of Acinetobacter baumannii isolates
reported recently by Galac and coworkers (MR Galac, E. Snesrud, F. Lebreton, J. Stam, et …

Identification of further variation at the lipooligosaccharide outer core locus in Acinetobacter baumannii genomes and extension of the OCL reference sequence …

BM Sorbello, SM Cahill, JJ Kenyon - Microbial Genomics, 2023 - microbiologyresearch.org
The outer core locus (OCL) that includes genes for the synthesis of the variable outer core
region of the lipooligosaccharide (LOS) is one of the key epidemiological markers used for …

Identification of Acinetobacter baumannii loci for capsular polysaccharide (KL) and lipooligosaccharide outer core (OCL) synthesis in genome assemblies using curated …

KL Wyres, SM Cahill, KE Holt, RM Hall… - Microbial …, 2019 - microbiologyresearch.org
Multiply antibiotic-resistant Acinetobacter baumannii infections are a global public health
concern and accurate tracking of the spread of specific lineages is needed. Variation in the …

An update to the database for Acinetobacter baumannii capsular polysaccharide locus typing extends the extensive and diverse repertoire of genes found at and …

SM Cahill, RM Hall, JJ Kenyon - Microbial Genomics, 2022 - microbiologyresearch.org
Several novel non-antibiotic therapeutics for the critical priority bacterial pathogen,
Acinetobacter baumannii, rely on specificity to the cell-surface capsular polysaccharide …

Variation in the OC Locus of Acinetobacter baumannii Genomes Predicts Extensive Structural Diversity in the Lipooligosaccharide

JJ Kenyon, SJ Nigro, RM Hall - PloS one, 2014 - journals.plos.org
Lipooligosaccharide (LOS) is a complex surface structure that is linked to many pathogenic
properties of Acinetobacter baumannii. In A. baumannii, the genes responsible for the …

Revised structure of the capsular polysaccharide of Acinetobacter baumannii LUH5533 (serogroup O1) containing di-N-acetyllegionaminic acid

AS Shashkov, SN Senchenkova, AV Popova… - Russian Chemical …, 2015 - Springer
A glycopolymer classified as an O-specific polysaccharide had earlier been isolated from the
multi-drug resistant nosocomial pathogen Acinetobacter baumannii LUH5533 (serogroup …

The KL24 gene cluster and a genomic island encoding a Wzy polymerase contribute genes needed for synthesis of the K24 capsular polysaccharide by the multiply …

JJ Kenyon, AA Kasimova, MM Shneider… - …, 2017 - microbiologyresearch.org
The whole-genome sequence of the multiply antibiotic resistant Acinetobacter baumannii
isolate RCH51 belonging to sequence type ST103 (Institut Pasteur scheme) revealed that …

Variation in the Complex Carbohydrate Biosynthesis Loci of Acinetobacter baumannii Genomes

JJ Kenyon, RM Hall - PloS one, 2013 - journals.plos.org
Extracellular polysaccharides are major immunogenic components of the bacterial cell
envelope. However, little is known about their biosynthesis in the genus Acinetobacter …

Acinetobacter baumannii K20 and K21 capsular polysaccharide structures establish roles for UDP-glucose dehydrogenase Ugd2, pyruvyl transferase Ptr2 and two …

AA Kasimova, JJ Kenyon, NP Arbatsky… - …, 2018 - academic.oup.com
Infections caused by Acinetobacter baumannii isolates from the major global clones, GC1
and GC2, are difficult to treat with antibiotics, and phage therapy, which requires extensive …

Genomic and Phenotypic Analyses of Acinetobacter baumannii Isolates From Three Tertiary Care Hospitals in Thailand

J Loraine, E Heinz, R Soontarach… - Frontiers in …, 2020 - frontiersin.org
Antibiotic resistant strains of Acinetobacter baumannii are responsible for a large and
increasing burden of nosocomial infections in Thailand and other countries of Southeast …