Neonatal exposure to drugs in breast milk
PJ McNamara, M Abbassi - Pharmaceutical research, 2004 - Springer
There are many benefits of breast-feeding both for the infant and for the mother. Nursing
mothers who are also taking medications or exposed to environmental hazards may be …
mothers who are also taking medications or exposed to environmental hazards may be …
Using pharmacokinetics to predict the effects of pregnancy and maternal–infant transfer of drugs during lactation
GD Anderson - Expert opinion on drug metabolism & toxicology, 2006 - Taylor & Francis
Knowledge of pharmacokinetics and the use of a mechanistic-based approach can improve
our ability to predict the effects of pregnancy for medications when data are limited. Despite …
our ability to predict the effects of pregnancy for medications when data are limited. Despite …
Studying drugs in human milk: time to unify the approach
EJ Begg, SB Duffull, LP Hackett… - Journal of Human …, 2002 - journals.sagepub.com
The trend globally for mothers to breastfeed has highlighted the need for information on drug
transfer into breast milk and the extent to which the suckling neonate may be exposed and …
transfer into breast milk and the extent to which the suckling neonate may be exposed and …
Infant drug exposure via breast milk
RHJ Verstegen, PO Anderson… - British Journal of Clinical …, 2022 - Wiley Online Library
More than half of women take medications during breastfeeding, predisposing their infants
to medication exposure via breast milk. As a result, adverse drug reactions may emerge in …
to medication exposure via breast milk. As a result, adverse drug reactions may emerge in …
Drugs in lactation
RHJ Verstegen, S Ito - Journal of Obstetrics and Gynaecology …, 2019 - Wiley Online Library
Although most medications can be taken safely during breastfeeding, potential risks of infant
toxicity do exist because all medications will be excreted into the breast milk to some extent …
toxicity do exist because all medications will be excreted into the breast milk to some extent …
Drug excretion into breast milk—overview
S Ito, A Lee - Advanced drug delivery reviews, 2003 - Elsevier
Breastfeeding is the optimal form of infant feeding for the first months of an infant's life, and
the majority of healthy women initiate breastfeeding after the birth of their infant. However …
the majority of healthy women initiate breastfeeding after the birth of their infant. However …
Clinical lactation studies and the role of pharmacokinetic modeling and simulation in predicting drug exposures in breastfed infants
PO Anderson, JD Momper - Journal of Pharmacokinetics and …, 2020 - Springer
The relative lack of information on medication use during breastfeeding is an ongoing
problem for health professionals and mothers alike. Most nursing mothers are prescribed …
problem for health professionals and mothers alike. Most nursing mothers are prescribed …
[HTML][HTML] Drug distribution in human milk
KF Ilett, JH Kristensen… - Australian …, 1997 - australianprescriber.tg.org.au
Assessing the safety of breast feeding during maternal drug therapy is an individualised risk:
benefit analysis. An infant's exposure depends on drug transfer into milk, daily milk intake …
benefit analysis. An infant's exposure depends on drug transfer into milk, daily milk intake …
Drugs in human milk: clinical pharmacokinetic considerations
HC Atkinson, EJ Begg, BA Darlow - Clinical pharmacokinetics, 1988 - Springer
Drugs ingested by a lactating mother would be expected to appear in human milk to some
extent and be ingested by a breast-feeding infant. Drugs pass from maternal plasma into …
extent and be ingested by a breast-feeding infant. Drugs pass from maternal plasma into …
Non-clinical models to determine drug passage into human breast milk
Background: Successful practice of clinical perinatal pharmacology requires a thorough
understanding of the pronounced physiological changes during lactation and how these …
understanding of the pronounced physiological changes during lactation and how these …