A 3D numerical study of the effect of channel height on leukocyte deformation and adhesion in parallel-plate flow chambers

DB Khismatullin, GA Truskey - Microvascular research, 2004 - Elsevier
The effect of channel height on leukocyte adhesion to a lower plate in a parallel-plate flow
chamber is studied by direct numerical simulations in three dimensions. The numerical …

Plasma release cell layering theory for blood flow

GB Thurston - Biorheology, 1989 - content.iospress.com
Significant internal structural changes occur in flowing blood when shear strain exceeds the
critical value of 1 (unit strain), forcing alignment of the erythrocytes and releasing trapped …

Effects of shear rate, confinement, and particle parameters on margination in blood flow

M Mehrabadi, DN Ku, CK Aidun - Physical Review E, 2016 - APS
The effects of flow and particle properties on margination of particles in red blood cell (RBC)
suspensions is investigated using direct numerical simulation (DNS) of cellar blood flow. We …

Large deformation of red blood cell ghosts in a simple shear flow

CD Eggleton, AS Popel - Physics of fluids, 1998 - pubs.aip.org
The membrane of the red blood cell RBC is easily deformed by shearing forces while
maintaining its local area nearly unchanged. This type of response is due to the structure of …

Leukocyte margination in a model microvessel

JB Freund - Physics of fluids, 2007 - pubs.aip.org
The physiological inflammation response depends upon the multibody interactions of blood
cells in the microcirculation that bring leukocytes (white blood cells) to the vessel walls. We …

A low-dimensional model for the red blood cell

W Pan, B Caswell, GE Karniadakis - Soft matter, 2010 - pubs.rsc.org
The red blood cell (RBC) is an important determinant of the rheological properties of blood
because of its predominant number density, special mechanical properties and dynamics …

Shear-induced particle migration and margination in a cellular suspension

H Zhao, ESG Shaqfeh, V Narsimhan - Physics of Fluids, 2012 - pubs.aip.org
We simulate the cross-flow migration of rigid particles such as platelets in a red blood cell
(RBC) suspension using the Stokes flow boundary integral equation method. Two types of …

The interaction of leukocytes and erythrocytes in capillary and postcapillary vessels

GW Schmid-Schönbein, S Usami, R Skalak… - Microvascular …, 1980 - Elsevier
In capillaries white blood cells tend to flow with a lower velocity than red blood cells. This is
due to the larger volume of the white cells and their spherical shape as compared to that of …

Blood flow and red blood cell deformation in nonuniform capillaries: effects of the endothelial surface layer

TW Secomb, R Hsu, AR Pries - Microcirculation, 2002 - Taylor & Francis
Objective: A theoretical model is used to examine the mechanics of red blood cell (RBC)
motion in nonuniform capillaries. The model includes effects of the endothelial surface layer …

Role of erythrocytes in leukocyte-endothelial interactions: mathematical model and experimental validation

LL Munn, RJ Melder, RK Jain - Biophysical journal, 1996 - cell.com
The binding of circulating cells to the vascular wall is a central process in inflammation,
metastasis, and therapeutic cell delivery. Previous in vitro studies have identified the …