Background Adipose tissue glucose uptake is impaired in insulin-resistant states, but ex vivo
studies of human adipose tissue have yielded heterogeneous results. This discrepancy may …

Objective Insulin resistance is reflected by the rates of reduced glucose uptake (GU) into the
key insulin-sensitive tissues, skeletal muscle, liver and adipose tissue. It is unclear whether …

Background and Aims: Although whole-body insulin resistance in obesity is established,
information on insulin action in peripheral tissues, especially adipose tissue (AD), is limited …

To elucidate the role of adipose tissue glucose uptake in whole-body metabolism, sc and
visceral adipose tissue glucose uptake and perfusion were measured in 10 nonobese and …

After food ingestion, macronutrients are transported to and stored in the skeletal muscle and
adipose tissue. They can be subsequently used as an energy source in times of energy …

The kinetics of in vivo insulin-mediated glucose uptake in human obesity have not been
previously studied. To examine this, we used the glucose-clamp technique to measure …

To define the kinetic mechanisms of insulin resistance (IR) in insulin-dependent diabetes
(IDDM), we studied seven control (C) and five IDDM (glycohemoglobin, 14±2%) men …

Objective: Insulin resistance in obese subjects results in the impaired use of glucose by
insulin‐sensitive tissues, eg, skeletal muscle. In the present study, we determined whether …

Rats fed a high-fat diet display blunted insulin-stimulated skeletal muscle glucose uptake. It
is not clear whether this is due solely to a defect in glucose transport, or if glucose delivery …

We have observed that in vitro incubated human muscle fiber strips from obese patients with
or without non-insulin-dependent diabetes mellitus (NIDDM) have reduced insulin …