Polyamines are important multifunctional cellular components and are classically
considered as mediators of cell growth and division. Recently polyamines have been also …

The natural polyamines putrescine, spermidine and spermine are in multiple ways involved
in cell growth and the maintenance of cell viability. In the course of the last 15 years more …

The natural polyamines (putrescine, spermidine and spermine) are ubiquitous low-
molecular aliphatic amines that play multifunctional roles in cell growth and differentiation …

The natural polyamines spermine, spermidine and putrescine, polycationic molecules at
physiological pH, interact with mitochondrial membranes at two specific binding sites …

Growing evidence suggests a role for polyamines in apoptosis, although the relationship
appears to be complex. α-Difluoromethylornithine (DFMO), a largely used ornithine …

Polyamines, namely putrescine, spermidine, and spermine, are essential for cell survival
and proliferation. A decrease in intracellular polyamine levels is associated with apoptosis …

Polyamines are ubiquitous organic cations required for cell proliferation. However, some
evidence suggested that their excessive accumulation can induce apoptosis. We show here …

Polyamines are involved in the regulation of cellular growth and survival by interacting with
processes like translation, transcription or ion transport. The aim of our study was to analyze …

Polyamines are aliphatic cations with multiple functions and are essential for life. Cellular
polyamine levels are regulated by multiple pathways such as synthesis from amino acid …

Intracellular polyamine homeostasis is important for the regulation of cell proliferation and
apoptosis and is necessary for the balanced growth of cells and tissues. Polyamines have …