Combined finasteride and flutamide therapy in men with advanced prostate cancer

DK Ornstein, GS Rao, B Johnson, ET Charlton… - Urology, 1996 - Elsevier
OBJECTIVES: To evaluate the efficacy of combined finasteride and flutamide therapy in men
with advanced prostate cancer by determining (1) the short-term tolerability of finasteride …

Frequency of flutamide induced hepatotoxicity in patients with prostate carcinoma

M Çetin, D Demirci, A Ünal, M Altinbaş… - Human & …, 1999 - journals.sagepub.com
To identify and describe the frequency and severity of hepatotoxicity in patients who
received flutamide therapy for prostate cancer, 22 patients were treated with the combination …

Flutamide-associated liver toxicity during treatment with total androgen suppression and radiation therapy for prostate cancer.

SA Rosenthal, DE Linstadt, MH Leibenhaut, EJ Andras… - Radiology, 1996 - pubs.rsna.org
PURPOSE: To examine the frequency and severity of toxicity associated with flutamide
inpatients treated with total androgen suppression before and during pelvic radiation …

An intraprostatic modified release formulation of antiandrogen 2-hydroxyflutamide for localized prostate cancer

TL Tammela, M Häggman, S Ladjevardi… - The Journal of …, 2017 - auajournals.org
Purpose: We investigated the tolerability, safety and antitumor effects of a novel
intraprostatic depot formulation of antiandrogen 2-hydroxyflutamide (in NanoZolid®) in men …

Clinical utility of ursodeoxycholic acid in preventing flutamide‐induced hepatopathy in patients with prostate cancer: A preliminary study

M Kojima, K Kamoi, O Ukimura, A Fujito… - … journal of urology, 2002 - Wiley Online Library
Background: The present study was designed to ascertain retrospectively the validity of
ursodeoxycholic acid (UDCA) in the treatment of prostate cancer in terms of prophylactic …

Bicalutamide for advanced prostate cancer: the natural versus treated history of disease.

HI Scher, C Liebertz, WK Kelly, M Mazumdar… - Journal of clinical …, 1997 - ascopubs.org
PURPOSE To determine the therapeutic effects of bicalutamide 200 mg in patients with
prostate cancers of different hormone sensitivities. METHODS Patients with progressive …

Short term effects of flutamide administration on hypothalamic-pituitary-testicular axis in man

R Migliari, S Balzano, RM Scarpa, G Campus… - The Journal of …, 1988 - auajournals.org
The effect of short term administration of flutamide on the hypothalamic-pituitary-gonadal
axis was studied in six patients with advanced prostate cancer (C2 stage). Flutamide …

A phase II study of nilutamide in men with prostate cancer after the failure of flutamide or bicalutamide therapy

NB Davis, CW Ryan, WM Stadler… - BJU …, 2005 - Wiley Online Library
OBJECTIVE To determine the prostate‐specific antigen (PSA) response and time to PSA or
radiographic progression in men with prostate cancer refractory to bicalutamide and/or …

Hormone/antihormone withdrawal and dexamethasone for hormone‐refractory prostate cancer

T Nishiyama, M Terunuma - International journal of urology, 1998 - Wiley Online Library
Background Flutamide withdrawal has been reported to benefit patients with hormone‐
refractory prostate cancer. Several studies have also demonstrated that a combination of …

Flutamide as an alternative anti-androgen agent and predictor of the efficacy of novel androgen receptor-targeted agents

N Yamaguchi, S Morizane, T Yumioka… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: There are few reports that verify the relationship between the therapeutic
effects of flutamide and novel androgen receptor-targeted agents. We aimed to evaluate the …