New drugs approved for acute myeloid leukaemia in 2018

S Kucukyurt, AE Eskazan - British Journal of Clinical …, 2019 - Wiley Online Library
Acute myeloid leukaemia (AML) is a haematopoietic stem cell disorder, that is characterized
by the clonal expansion of myeloid blasts and suppression of normal haematopoiesis. The …

Updates on targeted therapies for acute myeloid leukaemia

S Kayser, MJ Levis - British journal of haematology, 2022 - Wiley Online Library
In the past few years research in the underlying pathogenic mechanisms of acute myeloid
leukaemia (AML) has led to remarkable advances in our understanding of the disease …

New and emerging therapies for acute myeloid leukaemia

JR Davis, DJ Benjamin… - Journal of Investigative …, 2018 - journals.sagepub.com
The treatment of acute myeloid leukemia (AML) has remained relatively unchanged for the
past 3–4 decades with generally poor outcomes, especially in elderly populations unfit for …

New targeted agents in acute myeloid leukemia: new hope on the rise

SR Bohl, L Bullinger, FG Rücker - International journal of molecular …, 2019 - mdpi.com
The therapeutic approach for acute myeloid leukemia (AML) remains challenging, since
over the last four decades a stagnation in standard cytotoxic treatment has been observed …

New treatment options for acute myeloid leukemia in 2019

M Cerrano, R Itzykson - Current oncology reports, 2019 - Springer
Abstract Purpose of Review The extensive genomic characterization of acute myeloid
leukemia (AML) led to the identification of a vast number of potential therapeutic targets. We …

[HTML][HTML] Recently approved therapies in acute myeloid leukemia: a complex treatment landscape

C Talati, K Sweet - Leukemia research, 2018 - Elsevier
Acute myeloid leukemia (AML) is a heterogeneous disease. Until recently, treatment for
patients with AML was limited to induction chemotherapy with cytarabine and anthracycline …

How I treat acute myeloid leukemia in the era of new drugs

CD DiNardo, AH Wei - Blood, The Journal of the American …, 2020 - ashpublications.org
The acute myeloid leukemia (AML) treatment landscape has changed substantially since
2017. New targeted drugs have emerged, including venetoclax to target B-cell lymphoma 2 …

Recent drug approvals for acute myeloid leukemia

C Lai, K Doucette, K Norsworthy - Journal of hematology & oncology, 2019 - Springer
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with an
incidence that increases with age, and a generally poor prognosis. The disease is clinically …

New agents for acute myeloid leukemia: is it time for targeted therapies?

F Ferrara - Expert opinion on investigational drugs, 2012 - Taylor & Francis
Introduction: The prognosis of acute myeloid leukemia (AML) is improved in the last two
decades, even though induction and consolidation chemotherapy has not involved new …

New treatment options for older patients with acute myeloid leukemia

K Saxena, M Konopleva - Current treatment options in oncology, 2021 - Springer
Opinion statement The treatment of acute myeloid leukemia (AML) has evolved considerably
over the past several years. Advances in the field have historically benefited younger …