D-dimer levels at diagnosis and long-term clinical outcomes in venous thromboembolism: from the COMMAND VTE Registry

M Oi, Y Yamashita, M Toyofuku, T Morimoto… - Journal of Thrombosis …, 2020 - Springer
The relationship between D-dimer level at diagnosis and long-term clinical outcomes has
not been fully evaluated in venous thromboembolism (VTE). The COMMAND VTE Registry …

Potential impact of adjusting the threshold of the quantitative D‐dimer based on pretest probability of acute pulmonary embolism

C Kabrhel, D Mark Courtney… - Academic …, 2009 - Wiley Online Library
Objectives: The utility of D‐dimer testing for suspected pulmonary embolism (PE) can be
limited by test specificity. The authors tested if the threshold of the quantitative D‐dimer can …

Diagnostic value of D-dimer in patients with suspected pulmonary embolism: results from a multicentre outcome study

F Parent, S Maître, G Meyer, C Raherison, H Mal… - Thrombosis research, 2007 - Elsevier
BACKGROUND: D-dimer tests are used in various diagnostic strategies to exclude
pulmonary embolism (PE). However, their role as an exclusionary first-line test is still …

Risk stratification and clinical outcomes in patients with acute pulmonary embolism

CM Huang, YC Lin, YJ Lin, SL Chang, LW Lo, YF Hu… - Clinical …, 2011 - Elsevier
OBJECTIVES: Pulmonary embolism is a common disease associated with a high mortality
rate. The risk assessment and appropriate treatment selection of patients with acute …

[HTML][HTML] Is stand‐alone D‐dimer testing safe to rule out acute pulmonary embolism?

N Van Es, T Van der Hulle, HR Büller, FA Klok… - Journal of Thrombosis …, 2017 - Elsevier
Essentials• A stand‐alone D‐dimer below 750 μg/L has been proposed to rule out acute
pulmonary embolism (PE).• This was a post‐hoc analysis on data from 6 studies comprising …

Rapid ELISA assay for plasma D-dimer in the diagnosis of segmental and subsegmental pulmonary embolism

PE Sijens, HE Van Ingen, EJR Van Beek… - Thrombosis and …, 2000 - thieme-connect.com
Study objective To assess the accuracy of a rapid ELISA D-dimer assay for the exclusion of
pulmonary embolism (PE) in patients suspected of PE, using pulmonary angiography alone …

Relationship between baseline D-dimer and prognosis in Japanese patients with venous thromboembolism: Insights from the J'xactly study

S Migita, Y Okumura, I Fukuda, M Nakamura… - Frontiers in …, 2023 - frontiersin.org
Background D-dimer is a biomarker of fibrin production and degradation, and changes in D-
dimer concentration suggest fibrin clot formation, which is associated with thromboembolism …

Predictive value of high-sensitivity troponin I and D-dimer assays for adverse outcome in patients with acute pulmonary embolism

T Walter, P Apfaltrer, F Weilbacher… - Experimental and …, 2013 - spandidos-publications.com
High-sensitivity troponin (hs-cTn) assays enable the troponin cutoff value to be lowered,
resulting in an increase of sensitivity at the cost of specificity. In the present study, the risk of …

D-Dimer testing in pulmonary embolism with a focus on potential Pitfalls: a Narrative review

L Wauthier, J Favresse, M Hardy, J Douxfils, G Le Gal… - Diagnostics, 2022 - mdpi.com
D-dimer is a multifaceted biomarker of concomitant activation of coagulation and fibrinolysis,
which is routinely used for ruling out pulmonary embolism (PE) and/or deep vein thrombosis …

Risk factors for pulmonary embolism in patients preliminarily diagnosed with community-acquired pneumonia: a prospective cohort study

Y Zhang, Q Zhou, Y Zou, X Song, S Xie, M Tan… - Journal of thrombosis …, 2016 - Springer
D-dimer levels are increased in patients with acute pulmonary embolism (PE). However, D-
dimer levels are also increased in patients with community-acquired pneumonia (CAP). The …