In addition to its essential functions within the cytoskeleton, actin also localizes to the cell
nucleus, where it is linked to many important nuclear processes from gene expression to …

The nuclear actin-related proteins (ARPs) share overall structure and low-level sequence
homology with conventional actin. They are indispensable subunits of macromolecular …

β-Actin, once thought to be an exclusively cytoplasmic protein, is now known to have
important functions within the nucleus. Nuclear β-actin associates with and functions in …

Actin is one of the most abundant eukaryotic cytoskeletal polymer-forming proteins, which, in
the filamentous form, regulates a number of physiological processes, ranging from cell …

The mystery of nuclear actin has puzzled biologists for decades largely due to the lack of
defined experimental systems. However, the development of actin-containing chromatin …

Background Post-transcriptional RNA regulons ensure coordinated expression of
monocistronic mRNAs encoding functionally related proteins. In this study, we employ a …

Members of the actin family have well-characterized cytoskeletal functions, but actin and
actin-related proteins (ARPs) have also been implicated in nuclear activities. Previous …

The dynamic interchange between monomeric globular actin (G-actin) and polymeric
filamentous actin filaments (F-actin) is fundamental and essential to many cellular …

In the recent years, the role of actin and actin-binding proteins in gene transcription has
received considerable attention. Nuclear monomeric and polymerized actin and several …

The actins are essential cytoskeletal proteins required for the survival and growth of cells.
The transitions between soluble (G-actin) and filamentous (F-actin) forms of actin (actin …