Background Uterine leiomyoma is the most common benign tumor in reproductive-age
women. Each leiomyoma is thought to be a benign monoclonal tumor arising from a single …

Uterine leiomyomas (also known as uterine fibroids) are the most common benign tumors of
female reproductive tract and are the single most common indication for hysterectomies …

Context: Uterine leiomyoma is the most common benign tumor in reproductive-age women.
Using a dye-exclusion technique, we previously identified a side population of leiomyoma …

Although the etiology of leiomyoma is unclear, a progenitor/undifferentiated cell population
has been described whose dysregulation may be involved in the onset of uterine conditions …

Uterine leiomyomas are extremely common estrogen and progesterone-dependent tumors
of the myometrium and cause irregular uterine bleeding, severe anemia, and recurrent …

Tissue-specific (or somatic) stem cells constitute a subset of cells residing in normal adult
tissues. By undergoing asymmetric division, they retain their ability to self-renew while …

Uterine leiomyomas (fibroids) represent the most common class of benign tumors in women.
Multiple leiomyomas usually arise from the uterus of a symptomatic woman. These tumors …

BACKGROUND Uterine leiomyoma is the most common benign tumor in women and is
thought to arise from the clonal expansion of a single myometrial smooth muscle cell …

Recent genomic studies have identified subtypes of uterine leiomyoma (LM) with distinctive
genetic alterations. Here, we report the elucidation of the biological characteristics of the two …

STUDY QUESTION What are the cellular composition and single-cell transcriptomic
differences between myometrium and leiomyomas as defined by single-cell RNA …