[HTML][HTML] The adult cystic fibrosis airway microbiota is stable over time and infection type, and highly resilient to antibiotic treatment of exacerbations
Cystic fibrosis (CF) is characterized by defective mucociliary clearance and chronic airway
infection by a complex microbiota. Infection, persistent inflammation and periodic episodes …
infection by a complex microbiota. Infection, persistent inflammation and periodic episodes …
Cystic fibrosis respiratory microbiota: unraveling complexity to inform clinical practice
LJ Caverly, JJ LiPuma - Expert review of respiratory medicine, 2018 - Taylor & Francis
Introduction: Cystic fibrosis (CF) lung disease is characterized by chronic cycles of
pulmonary infection, inflammation, and mucus obstruction, beginning early in life, and …
pulmonary infection, inflammation, and mucus obstruction, beginning early in life, and …
[HTML][HTML] Lung function and microbiota diversity in cystic fibrosis
Background Chronic infection and concomitant airway inflammation is the leading cause of
morbidity and mortality for people living with cystic fibrosis (CF). Although chronic infection in …
morbidity and mortality for people living with cystic fibrosis (CF). Although chronic infection in …
The airway microbiome in COPD, bronchiectasis and bronchiectasis‐COPD overlap
PY Tiew, TK Jaggi, LLY Chan… - The Clinical …, 2021 - Wiley Online Library
Objective To review the airway microbiome in chronic obstructive pulmonary disease
(COPD), bronchiectasis and bronchiectasis‐COPD overlap (BCO). Data source and study …
(COPD), bronchiectasis and bronchiectasis‐COPD overlap (BCO). Data source and study …
Use of culture and molecular analysis to determine the effect of antibiotic treatment on microbial community diversity and abundance during exacerbation in patients …
Background Anaerobic bacteria are increasingly regarded as important in cystic fibrosis (CF)
pulmonary infection. The aim of this study was to determine the effect of antibiotic treatment …
pulmonary infection. The aim of this study was to determine the effect of antibiotic treatment …
The cystic fibrosis airway microbiome
Repeated pulmonary exacerbation and progressive lung function decline characterize cystic
fibrosis (CF) disease, and represents one of the leading causes of mortality in this patient …
fibrosis (CF) disease, and represents one of the leading causes of mortality in this patient …
[HTML][HTML] Relationship between airway dysbiosis, inflammation and lung function in adults with cystic fibrosis
Airway dysbiosis has been associated with lung disease severity in patients with cystic
fibrosis (CF). However, the relationship between dysbiosis, airway inflammation and lung …
fibrosis (CF). However, the relationship between dysbiosis, airway inflammation and lung …
[HTML][HTML] The airway microbiota in cystic fibrosis: a complex fungal and bacterial community—implications for therapeutic management
Background Given the polymicrobial nature of pulmonary infections in patients with cystic
fibrosis (CF), it is essential to enhance our knowledge on the composition of the microbial …
fibrosis (CF), it is essential to enhance our knowledge on the composition of the microbial …
Airway microbiota across age and disease spectrum in cystic fibrosis
ET Zemanick, BD Wagner… - European …, 2017 - Eur Respiratory Soc
Our objectives were to characterise the microbiota in cystic fibrosis (CF) bronchoalveolar
lavage fluid (BALF), and determine its relationship to inflammation and disease status. BALF …
lavage fluid (BALF), and determine its relationship to inflammation and disease status. BALF …
Sputum microbiota is predictive of long-term clinical outcomes in young adults with cystic fibrosis
Background Complex polymicrobial communities infect cystic fibrosis (CF) lower airways.
Generally, communities with low diversity, dominated by classical CF pathogens, associate …
Generally, communities with low diversity, dominated by classical CF pathogens, associate …