Rationale: Eradication and suppression of Pseudomonas aeruginosa is a key priority in
national guidelines for bronchiectasis and is a major focus of drug development and clinical …

Little is known about the microbiota shift induced by exacerbation in chronic obstructive
pulmonary disease (COPD) patients. The sputa microbiota of COPD patients was evaluated …

Background Exacerbations are crucial events during bronchiectasis progression. Objectives
To explore the associations between bacterial, viral, and bacterial plus viral isolations and …

Background Chronic obstructive pulmonary disease (COPD) frequent exacerbators (FE)
suffer increased morbidity and mortality compared to infrequent exacerbators (IE). The …

Background The respiratory microbiome is altered in COPD patients but its relationship with
core components of the disease, such as the severity of airflow limitation, the frequency of …

Dysbiotic airway microbiota play important roles in the inflammatory progression of asthma,
and exploration of airway microbial interactions further elucidates asthma pathogenesis …

Studying respiratory illness-specific microbial signatures and their interaction with other
micro-residents could provide a better understanding of lung microbial ecology. Each …

A growing body of literature has demonstrated relationships between the composition of the
airway microbiota (mixed-species communities of microbes that exist in the respiratory tract) …

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder with a
course that is not uniform for all COPD patients. Although smoking is considered as the …

Increasing evidence suggests that the lung microbiome plays an important role in chronic
obstructive pulmonary disease (COPD) severity. However, the dynamics of the lung …