Safety of intravenous valproate

O Devinsky, I Leppik, L James Willmore… - Annals of Neurology …, 1995 - Wiley Online Library
This multicenter, open‐label trial was designed to study the safety of intravenous (IV) sodium
valproate in patients with epilepsy. All 318 patients (previously treated with antiepileptic …

[HTML][HTML] First manic episode due to discontinuation of valproic acid in a patient with epilepsy

A Köksal, AC Dirican, Y Altunkaynak… - The Journal of …, 2014 - Am Neuropsych Assoc
Discussion The most common treatment strategy is using the appropriate AED for seizure
control as monotherapy in the lowest effective dosage throughout pregnancy. 2 VA acid …

[PDF][PDF] Hyponatremia associated with repeated use of sodium valproate

MH Orum, A Kalenderoglu, OB Egilmez… - Psychiatry and …, 2018 - researchgate.net
However, after 2 months of being discharged, he presented to the emergency service with
similar complaints. Changes in sodium and potassium levels were observed. He described …

Valproate-induced hyperammonemic encephalopathy: a case report and brief review of the literature

KK Sunkavalli, FM Iqbal, B Singh… - American Journal of …, 2013 - journals.lww.com
Almost 50 years after its discovery, valproic acid remains a mainstay in the treatment of
epilepsy, both alone and in combination with other anticonvulsants. It is also associated with …

Absence seizures aggravated by valproic acid

T Lerman‐Sagie, N Watemberg, U Kramer… - …, 2001 - Wiley Online Library
Purpose: To report on pediatric patients with absence epilepsy who experienced absence
seizure aggravation while receiving valproic acid (VPA). Methods: The charts of all children …

[PDF][PDF] Serious neurological complications of valproate therapy

S Zerjav, R Stowe - Psychopharmacol Newslett, 2007 - researchgate.net
Sodium valproate (VPA) is an anticonvulsant used in the treatment of epilepsy and bipolar
disorder. Most of its side effects are innocuous, such as transient sedation, an action and …

Probable valproate sodium-associated hypotension

KS Ota - The American Journal of Geriatric Pharmacotherapy, 2010 - Elsevier
Background: Valproate sodium, a commonly used antiepileptic drug (AED), is effective for
the treatment of status epilepticus and is often used as a second-line agent when other …

[PDF][PDF] Intravenous valproate for seizures in 137 Taiwanese children-valproate naive and non-naive

YC Chang, JJ Lin, HS Wang, ML Chou… - Acta Neurol …, 2010 - researchgate.net
Purpose: Valproate has been widely used in controlling various kinds of seizures.
Intravenous forms of valproate control seizures in a more rapid and efficacious pattern than …

Contribution of sodium valproate to the syndrome of inappropriate secretion of antidiuretic hormone

T Miyaoka, H Seno, M Itoga, T Kishi… - International clinical …, 2001 - journals.lww.com
We report the case of a 62-year-old man who was administered sodium valproate (VPA) and
who subsequently developed the syndrome of inappropriate secretion of antidiuretic …

Sodium valproate “encephalopathy”: report of three cases with generalised epilepsy

A Tartara, R Manni - The Italian Journal of Neurological Sciences, 1985 - Springer
A report of 3 cases of sodium valproate “encephalopathy”. The addition of valproate to the
treatment in 3 subjects, two adults and one child, all with generalised epilepsy, induced a …