Mucosal immunization has potential benefits over conventional parenteral immunization,
eliciting immune defense in both mucosal and systemic tissue for protecting from pathogen …

Vaccination remains a key tool in the protection and eradication of diseases. However, the
development of new safe and effective vaccines is not easy. Various live organism based …

New cationic nanoparticles (SMBV™) were evaluated for use as a nasal vaccine delivery
system for two recombinant proteins: HBsAg and β-galactosidase. Each protein was …

Many pathogens invade the host at the intestinal surface. To protect against these
enteropathogens, the induction of intestinal secretory IgA (SIgA) responses is paramount …

To develop protective immune responses against mucosal pathogens, the delivery route
and adjuvants for vaccination are important. The host, however, strives to maintain mucosal …

The use of peptides for various aspects of medical science has been a significant advance.
Peptide-based vaccines are promising, but weak immunogenic potency is impeding the …

Nasal delivery offers many benefits over traditional approaches to vaccine administration.
These include ease of administration without needles that reduces issues associated with …

It has long been known that protection against pathogens invading the organism via
mucosal surfaces correlates better with the presence of specific antibodies in local …

Vaccines represent the most relevant contribution of immunology to human health. However,
despite the remarkable success achieved in the past years, many vaccines are still missing …

Most infections occur at or through mucosal surfaces. Despite this knowledge, current
vaccination practices rely predominantly on parenteral administration with only a few …