Serotoninergic axonal contacts on identified cat spinal dorsal horn neurons and their correlation with nucleus raphe magnus stimulation

V Miletic, MJ Hoffert, MA Ruda… - Journal of …, 1984 - Wiley Online Library
This study examined the distribution of serotoninergic (5‐HT) immunoreactive axonal
contacts on spinal laminae I and II neurons by combining the intracellular horseradish …

Immunocytochemical identification of serotonin axonal contacts on characterized neurons in laminae I and II of the cat dorsal horn

MJ Hoffert, V Miletic, MA Ruda, R Dubner - Brain Research, 1983 - Elsevier
Serotonergic pathways from brainstem to spinal cord play an important role in the
modulation of pain perception. To establish where that modulation occurs, we examined …

Serotonin innervation of physiologically identified lamina I projection neurons

JLK Hylden, H Hayashi, MA Ruda, R Dubner - Brain research, 1986 - Elsevier
Physiologically characterized lamina I projection neurons, including antidromically activated
spinomesencephalic and spinothalamic tract cells, were intracellularly stained with HRP and …

Termination patterns of serotoninergic medullary raphespinal fibers in the rat lumbar spinal cord: an anterograde immunohistochemical study

SL Jones, AR Light - Journal of Comparative Neurology, 1990 - Wiley Online Library
Electrical and chemical stimulation given in the ventral medullary raphe nuclei inhibits spinal
nociceptive reflexes and spinal nociceptive transmission; serotoninergic receptors have …

Association of serotonin‐like immunoreactive axons with nociceptive projection neurons in the caudal spinal trigeminal nucleus of the rat

JL Li, T Kaneko, S Nomura, YQ Li… - Journal of Comparative …, 1997 - Wiley Online Library
Serotoninergic projections to the spinal dorsal horn are implicated in the modulation of
nociceptive transmission. However, morphological evidence indicating that serotoninergic …

Immunocytochemical analysis of serotonergic axons in laminae I and II of the lumbar spinal cord of the cat

MA Ruda, J Coffield, HW Steinbusch - Journal of Neuroscience, 1982 - Soc Neuroscience
Serotonergic axons in the superficial dorsal horn were examined at the light and electron
microscopic levels using an antibody specific for serotonin (5-HT). Immunoreactive 5-HT …

Serotonin immunoreactivity is contained in one physiological cell class in the rat rostral ventromedial medulla

SB Potrebic, HL Fields, P Mason - Journal of Neuroscience, 1994 - Soc Neuroscience
Neurons in the rostral ventromedial medulla (RVM) are the major source of serotonergic
projections to the dorsal horn. A large body of evidence implicates RVM serotonergic …

Axons which take up [3H] serotonin are presynaptic to enkephalin immunoreactive neurons in cat dorsal horn

EJ Glazer, AI Basbaum - Brain research, 1984 - Elsevier
Through combined ultrastructural localization of ENK immunoreactivity and [3 H] 5-HT
uptake sites, it was found that 5-HT radiolabeled axons contact ENK immunoreactive cell …

5-HT1A Receptors Mediate the Effect of the Bulbospinal Serotonin System on Spinal Dorsal Horn Nociceptive Neurons

FP Zemlan, AZ Murphy, MM Behbehani - Pharmacology, 1994 - karger.com
The present study examined whether the effect of stimulation of the nucleus raphe magnus
(NRM) is mediated by spinal cord dorsal horn serotonin1A (5-HT1A) receptors in the rat …

Physiological identification of pontomedullary serotonergic neurons in the rat

P Mason - Journal of neurophysiology, 1997 - journals.physiology.org
Mason, Peggy. Physiological identification of pontomedullary serotonergic neurons in the
rat. J. Neurophysiol. 77: 1087–1098, 1997. Spinal serotonin is derived entirely from bulbar …