OBJECTIVE To examine whether the effect of conventional lifestyle interventions on type 2
diabetes incidence differs by glucose-defined prediabetes phenotype. RESEARCH DESIGN …

Eur J Clin Invest 2011; 41 (6): 679–692 Abstract Background Recent genome‐wide
association studies enlarged our knowledge about the genetic background of type 2 …

Type 2 diabetes (T2D) and obesity are complex disorders that constitute major public health
problems. The evidence for familial aggregation of both T2D and obesity is substantial. To …

Background Type 2 diabetes mellitus (T2DM) comprises the vast majority of all diabetes
cases in adults, with alarmingly increasing prevalence over the past few decades worldwide …

Genome-wide association studies (GWAS) may have reached their limit of detecting
common type 2 diabetes (T2D)–associated genetic variation. We evaluated the performance …

Background Multiple genetic loci have been convincingly associated with the risk of type 2
diabetes mellitus. We tested the hypothesis that knowledge of these loci allows better …

Abstract Aims/Introduction This cohort study of middle‐aged Japanese participants
investigated the relationship between family history of diabetes, the incident risk of type 2 …

Aims/hypothesis The aim of this study was to use Mendelian randomisation (MR) to identify
the causal risk factors for type 2 diabetes. Methods We first conducted a review of meta …

Aims/hypothesis Identification of novel biomarkers for type 2 diabetes and their genetic
determinants could lead to improved understanding of causal pathways and improve risk …

Aims/hypothesis The aim of this study was to identify a dietary pattern associated with
diabetes-related biomarkers and to investigate whether this pattern is associated with the …