Preclinical evidence of berberine on non-alcoholic fatty liver disease: a systematic review and meta-analysis of animal studies

S Ren, X Ma, R Wang, H Liu, Y Wei, S Wei… - Frontiers in …, 2021 - frontiersin.org
As lifestyle and diet structure impact our health, non-alcoholic fatty liver disease (NAFLD) is
prevalent all over the world. Some phytomedicines containing berberine (BBR) have been …

The potential mechanisms of berberine in the treatment of nonalcoholic fatty liver disease

X Zhu, H Bian, X Gao - Molecules, 2016 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is a globally observed metabolic disease with high
prevalence both in adults and children. However, there is no efficient medication available …

A Comprehensive Insight into the Effect of Berberine on Nonalcoholic Fatty Liver Disease (NAFLD): A Systematic Review

A Karimi, M Vajdi, S Sanaie, S Akhlaghi… - Journal of Food …, 2023 - Wiley Online Library
Hepatic dysfunction is primarily caused by nonalcoholic fatty liver disease (NAFLD).
Recently, berberine (BBR) has attracted researchers' interest with its hepatic protective …

Berberine in Non-Alcoholic Fatty Liver Disease—A Review

A Koperska, A Wesołek, M Moszak, M Szulińska - Nutrients, 2022 - mdpi.com
The incidence of Non-Alcoholic Fatty Liver Disease (NAFLD) has been rapidly increasing
during the last decade. It is a relevant health problem that affects 25% of the general …

The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review

Q Nie, M Li, C Huang, Y Yuan, Q Liang, X Ma… - Journal of Translational …, 2024 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is becoming increasingly prevalent
worldwide, emerging as a significant health issue on a global scale. Berberine exhibits …

Update on berberine in nonalcoholic fatty liver disease

Y Liu, L Zhang, H Song, G Ji - … ‐Based Complementary and …, 2013 - Wiley Online Library
Berberine (BBR), an active ingredient from nature plants, has demonstrated multiple
biological activities and pharmacological effects in a series of metabolic diseases including …

Berberine prevents progression from hepatic steatosis to steatohepatitis and fibrosis by reducing endoplasmic reticulum stress

Z Zhang, B Li, X Meng, S Yao, L Jin, J Yang, J Wang… - Scientific reports, 2016 - nature.com
The histological spectrum of nonalcoholic fatty liver diseases (NAFLD) ranges from hepatic
steatosis to steatohepatitis and fibrosis. Berberine (BBR) is known for its therapeutic effect …

Berberine improves glucogenesis and lipid metabolism in nonalcoholic fatty liver disease

L Zhao, Z Cang, H Sun, X Nie, N Wang, Y Lu - BMC Endocrine Disorders, 2017 - Springer
Background Nonalcoholic fatty liver disease (NAFLD) is considered a critical hepatic
manifestation of metabolic syndrome. Berberine (BBR) exerts anti-hyperglycemic and anti …

Berberine ameliorates hepatic steatosis and suppresses liver and adipose tissue inflammation in mice with diet-induced obesity

T Guo, SL Woo, X Guo, H Li, J Zheng, R Botchlett… - Scientific reports, 2016 - nature.com
Increasing evidence demonstrates that berberine (BBR) is beneficial for obesity-associated
non-alcoholic fatty liver disease (NAFLD). However, it remains to be elucidated how BBR …

Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease—Clinical and Pre-Clinical Overview and Systematic Review of the Literature

F Ionita-Radu, C Patoni, AS Nancoff, FS Marin… - International Journal of …, 2024 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the predominant cause of chronic liver
conditions, and its progression is marked by evolution to non-alcoholic steatosis …