Objectives: Non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic
steatohepatitis (NASH) and hepatocarcinoma is a serious and growing problem. However …

Nonalcoholic fatty liver disease (NAFLD), ranging from simple steatosis to nonalcoholic
steatohepatitis (NASH), is a liver disease worldwide without approved therapeutic drugs …

The present study investigated the effects of berberine (BBR) on hepatic oxidative stress and
the nuclear factor erythroid 2‑related factor 2/antioxidant response element (Nrf2/ARE) …

Background Berberine (BBR), a natural compound extracted from Chinese herb, has been
shown to effectively attenuate nonalcoholic fatty liver disease (NAFLD) in clinic. However …

Alcoholic fatty liver disease (AFLD) is an early stage of alcohol-related liver disease
characterized by abnormal lipid metabolism in hepatocytes. To date, to our knowledge, there …

Objective: To investigate the effect of berberine (BBR) on intestinal barrier function in
nonalcoholic fat liver disease (NAFLD) in rats. Materials and Methods: Rats were divided …

The global incidence of nonalcoholic fatty liver disease (NAFLD) is increasing. The present
study explored the effect and mechanism of berberine (BBR) on NAFLD in rats. Thirty‑five …

Background Berberine (BBR) has been widely used to treat non-alcoholic fatty liver disease
(NAFLD). The metabolites of BBR were believed to contribute significantly to its …

Background We recently demonstrated a positive effect of berberine on nonalcoholic fatty
liver disease patients after 16 weeks of treatment by comparing mere lifestyle intervention in …

Inflammation plays an essential role in the pathogenesis of non-alcoholic fatty liver disease
(NAFLD). Berberine (BBR), an isoquinoline alkaloid isolated from Chinese medicinal herbs …