CD37 is a membrane protein of the tetraspanin superfamily, which includes CD9, CD53,
CD63, CD81, and CD82. Many of these molecules are expressed on leukocytes and have …

The human tetraspan molecule CD81 is a coreceptor in B and T cell activation and a
candidate receptor for hepatitis C virus infection. We examined the surface expression of …

Human leukocyte antigen B27 (HLA‐B27) is associated with protection in human
immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection. This protective role is …

The majority of people infected with hepatitis C virus (HCV) fail to generate or maintain a T-
cell response effective for viral clearance. Evidence from murine chronic viral infections …

Hepatitis C virus (HCV) recurrence after orthotopic liver transplantation (OLT) significantly
accelerates progression to allograft cirrhosis. Current biochemical parameters to monitor …

The tetraspanin superfamily member CD81 has been shown to form microdomains in the
plasma membrane and to participate in the recruitment of numerous adhesion molecules …

The immune response against hepatitis C virus (HCV) is rarely effective at clearing the virus,
resulting in∼ 170 million chronic HCV infections worldwide. Here we report that ligation of …

Hepatitis C virus (HCV)‐specific T cell responses are essential for HCV control, and chronic
infection is characterized by functionally altered antigen‐specific T cells. It has been …

Human and animal model evidence suggests that CD4+ T cells play a critical role in the
control of chronic hepatitis C virus (HCV) infection. However, despite their importance, the …

The identification of a specific immunogenic candidate that will effectively activate the
appropriate pathway for neutralizing antibody production is fundamental for vaccine design …