Orthodontic force produces mechanical irritation and inflammation in the periodontium,
which is inevitably accompanied by pain. Despite its prevalence, treatment of orthodontic …

Objective The aim of this study was to quantify the temporal changes in inflammation and
TRPA1, TRPV1 and CGRP expression in the trigeminal ganglion during force-induced …

Orthodontic pain has confused the orthodontics for a long time, and recent research
demonstrated that transient receptor potential vanilloid type 1 (TRPV1) had crucial functions …

Orthodontic force produces mechanical irritation and localized inflammation in the
periodontium, which causes pain in most patients. Nocifensive behaviors resulting from …

To investigate whether transient receptor potential vanilloid type 1 (TRPV 1) is involved in
pain induced by experimental tooth movement, experiments were performed in male S …

Despite the high incidence of dental pain, the mechanism underlying its generation is mostly
unknown. Functional expression of temperature-sensitive transient receptor potential …

Orthodontic pain that is induced by tooth movement is an important sequela of orthodontic
treatment and has a significant effect on patient quality of life. Studies have shown that the …

Background/Aim: The transient receptor potential vanilloid 1 (TRPV1) ion receptor is
involved in the release of calcitonin gene-related peptide (CGRP), a major contributor to …

Identification of potential therapeutic targets is needed for temporomandibular disorders
(TMD) pain, the most common form of orofacial pain, because current treatments lack …

Thermal and mechanical hypersensitivity in the injured region is a common complication.
Although it is well known clinically that thermal and mechanical sensitivity of the oral mucosa …