Beta amyloid plaques, neurofibrillary tangles, and impaired glucose metabolism are among
the most prevalent pathological characteristics of Alzheimer's disease (AD). However …

Recently developed positron emission tomography (PET) tracers, such as PIB and FDDNP,
help to visualize amyloid plaques and neurofibrillary tangles in living subjects. FDDNP binds …

Abstract Current Positron Emission Tomography (PET) biomarkers for Alzheimer's disease
(AD) assess either neuronal function, or associated pathological features of this common …

Deposition of amyloid plaques is believed to be a central event in the development of
Alzheimer's disease (AD). The present study was undertaken to evaluate statistical methods …

BACKGROUND: This is a progress report of the Alzheimer's Disease Neuroimaging Initiative
(ADNI) positron emission tomography (PET) Core. METHODS: The Core has supervised the …

In Alzheimer disease (AD), which is the most common cause of dementia, the underlying
disease pathology most probably precedes the onset of cognitive symptoms by many years …

Although diagnosing the syndrome of dementia is largely a clinical endeavor, neuroimaging
plays an increasingly important role in accurately determining the underlying etiology, which …

The purpose of this study was to compare the diagnostic accuracy of glucose metabolism
and amyloid deposition as demonstrated by 18F-FDG and Pittsburg Compound B (PiB) PET …

Abstract Background N-methyl [11C] 2-(4′ methylaminophenyl)-6-hydroxy-benzothiazole
(PIB) is a positron emission tomography (PET) tracer with amyloid binding properties which …

Objectives The aim of this article was to review the current role of brain PET in the diagnosis
of Alzheimer dementia. The characteristic patterns of glucose metabolism on brain FDG-PET …