Statin use during ischemic stroke hospitalization is strongly associated with improved poststroke survival

AC Flint, H Kamel, BB Navi, VA Rao, BS Faigeles… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Statins reduce infarct size in animal models of stroke and have
been hypothesized to improve clinical outcomes after ischemic stroke. We examined the …

[HTML][HTML] Rising statin use and effect on ischemic stroke outcome

SS Yoon, J Dambrosia, J Chalela, M Ezzeddine… - BMC medicine, 2004 - Springer
Abstract Background Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors)
have neuroprotective effects in experimental stroke models and are commonly prescribed in …

Discontinuation of statin therapy and clinical outcome after ischemic stroke

F Colivicchi, A Bassi, M Santini, C Caltagirone - Stroke, 2007 - Am Heart Assoc
Background and Purpose—The majority of patients with previous ischemic stroke are
expected to benefit significantly from long-term statin therapy. However, discontinuation of …

Association between acute statin therapy, survival, and improved functional outcome after ischemic stroke: the North Dublin Population Stroke Study

D Ní Chróinín, EL Callaly, J Duggan, Á Merwick… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Statins improve infarct volume and neurological outcome in
animal stroke models. We investigated the relationship between statin therapy and ischemic …

Clinical effectiveness of statin therapy after ischemic stroke: primary results from the statin therapeutic area of the patient-centered research into outcomes stroke …

EC O'Brien, MA Greiner, Y Xian, GC Fonarow… - Circulation, 2015 - Am Heart Assoc
Background—In patients with ischemic stroke, data on the real-world effectiveness of statin
therapy for clinical and patient-centered outcomes are needed to better inform shared …

Effect of pretreatment with statins on ischemic stroke outcomes

MJ Reeves, JW Gargano, Z Luo, AJ Mullard, BS Jacobs… - Stroke, 2008 - Am Heart Assoc
Background and Purpose—Statins reduce the risk of stroke in at-risk populations and may
improve outcomes in patients taking statins before an ischemic stroke (IS). Our objectives …

Statin administration prior to ischaemic stroke onset and survival: exploratory evidence from matched treatment–control study

S Aslanyan, CJ Weir, GT McInnes… - European journal of …, 2005 - Wiley Online Library
In addition to their lipid‐lowering effects, it has been speculated that statins may also have
beneficial effects on cerebral circulation and brain parenchyma during ischaemic stroke and …

Lack of statin therapy and outcomes after ischemic stroke: a population-based study

J Åivo, JO Ruuskanen, A Tornio, P Rautava, V Kytö - Stroke, 2023 - Am Heart Assoc
Background: Statin treatment is effective at preventing adverse vascular events after
ischemic stroke (IS). However, many patients fail to use statins after IS. We studied the …

Effects of statin intensity and adherence on the long-term prognosis after acute ischemic stroke

J Kim, HS Lee, CM Nam, JH Heo - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Statin is an established treatment for secondary prevention after
ischemic stroke. However, the effects of statin intensity and adherence on the long-term …

Statin therapy after first stroke reduces 10-year stroke recurrence and improves survival

HJ Milionis, S Giannopoulos, M Kosmidou… - Neurology, 2009 - AAN Enterprises
Objective: To determine whether statin therapy after hospital discharge affects ischemic
stroke recurrence and long-term mortality in patients admitted for a first-ever occurrence of …