Cytoprotective effect of Fridericia chica (Bonpl.) LG Lohmann extract associated with geranylgeraniol enriched-fraction from Bixa orellana L. on epithelial cells …

RJ Machado Júnior, JC Camilli, RT Basting… - Natural product …, 2023 - Taylor & Francis
Bisphosphonates are drugs used to treat bone disorders. The chronic use of
bisphosphonates is associated with the occurrence of medication-related osteonecrosis of …

Standardized Arrabidaea chica Extract Shows Cytoprotective Effects in Zoledronic Acid-Treated Fibroblasts and Osteoblasts

PM Wiziack Zago, IM Oliveira Sousa… - Clinical, cosmetic and …, 2020 - Taylor & Francis
Introduction Osteonecrosis of the jaw is a condition associated with intraoral ulceration and
bone necrosis induced by antiresorptive medications, such as zoledronic acid, a …

Bixa orellana L. by-products' fractions from an industrial process: antiproliferative activity on tumor cells and chemical profile

RT Basting, PMB Abreu, IMO Sousa… - Natural product …, 2021 - Taylor & Francis
This study evaluated the phytochemical characterization of Bixa orellana (BO extract)
unsaponifiable extract and resulting fractions (F fraction-FF, Geranyl fraction–GF and R …

Evaluation of cancer chemopreventive potentials of Bixa orellana L. leaf extract.

DL Ajaghaku, MN Okwor, NH Okorie, CJ Mbah - 2020 - cabidigitallibrary.org
Bixa orellana L.(Bixaceae) is used in ethnomedicine for its anticancer/antitumor effects. This
study evaluated the cancer chemopreventive mechanisms of B. orellana leaf extract. The …

In vivo effects of geranylgeraniol on the development of bisphosphonate-related osteonecrosis of the jaws

F Koneski, D Popovic-Monevska, I Gjorgoski… - Journal of Cranio …, 2018 - Elsevier
Background Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a complication of
the bisphosphonate (BP) treatment and its pathopysiology is still not fully understood. The …

The cytotoxic and apoptotic effects of Ferulago W. Koch extracts on various cancer cell lines

F Bakar-Ates, B Hoti, I Gurbuz, T Gunbatan… - Turkish Journal of …, 2021 - degruyter.com
Background The studies investigating the anticancer activities of natural products have
accelerated to produce new solutions in the face of increasing cancer cases. Various …

Cytoprotective, Antiproliferative, and Anti-Oxidant Potential of the Hydroethanolic Extract of Fridericia chica Leaves on Human Cancer Cell Lines Exposed to α- and β …

N Alvarez-Ortega, K Caballero-Gallardo, C Juan… - Toxins, 2023 - mdpi.com
Fridericia chica (Bignoniaceae) is a Colombian Caribbean plant with numerous health
benefits, including properties such as wound healing, immune system stimulation, and …

Fridericia platyphylla (Cham.) LG Lohmann root extract exerts cytotoxic and antiproliferative effects on gastric tumor cells and downregulates BCL-XL, BIRC5, and …

JM Serpeloni, AFL Specian… - Human & …, 2020 - journals.sagepub.com
Fridericia platyphylla (Cham.) LG Lohmann (FP) has cytotoxic, anti-inflammatory, and
analgesic properties. We aimed to characterize the cytotoxic and antiproliferative effects of …

Eriobotrya japonica hydrophilic extract modulates cytokines in normal tissues, in the tumor of Meth-A-fibrosarcoma bearing mice, and enhances their survival time

HA Alshaker, NA Qinna, F Qadan, M Bustami… - … and Alternative Medicine, 2011 - Springer
Background Cytokines play a key role in the immune response to developing tumors, and
therefore modulating their levels and actions provides innovative strategies for enhancing …

The five Ferulago species inhibited cell proliferation and induced apoptosis of A549, MCF-7, PC3 and SW480 cancer cells in vitro

İ Gurbuz, T Gunbatan, F Bakar-Ates, B Hoti, H Duman… - 3 Biotech, 2023 - Springer
In this study, it was aimed to evaluate the cytotoxic and apoptotic activities of ethanolic
extracts prepared from the roots of 5 Ferulago species [F. humilis Boiss., F. macrosciadia …