Congenital defects of neural tube closure (neural tube defects; NTDs) are among the
commonest and most severe disorders of the fetus and newborn. Disturbance of any of the …

The number of mouse mutants and strains with neural tube defects (NTDs) now exceeds
240, including 205 representing specific genes, 30 for unidentified genes, and 9 …

The molecular requirements for neural tube closure are complex. This is illustrated by the
occurrence of neural tube defects (NTDs) in many genetic mouse mutants, which implicate a …

BACKGROUND: The number of mouse mutants and strains with neural tube closure defects
(NTDs) now exceeds 190, including 155 involving known genes, 33 with unidentified genes …

Neural tube defects (NTDs) are severe congenital malformations affecting 1 in every 1000
pregnancies.'Open'NTDs result from failure of primary neurulation as seen in anencephaly …

Birth defects (congenital anomalies) are the leading cause of death in babies under 1 year
of age. Neural tube defects (NTD), with a birth incidence of approximately 1/1000 in …

The human neural tube defects (NTD), anencephaly, spina bifida and craniorachischisis,
originate from a failure of the embryonic neural tube to close. Human NTD are relatively …

The vertebrate central nervous system is a hollow structure that develops first as a flat sheet
of cells and subsequently rolls into a tube during embryogenesis. Failure of this rolling …

Neural tube defects (NTDs) represent a common group of severe congenital malformations
that result from failure of neural tube closure during early development. Their etiology is …

The embryonic development of mammalian neural tube defects - ScienceDirect Skip to
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