Genome-wide analysis of gene expression has been widely applied to study the
endometrium, although to our knowledge no systematic reviews have been performed …

STUDY QUESTION Are genetic effects on endometrial gene expression tissue specific
and/or associated with reproductive traits and diseases? SUMMARY ANSWER Analyses of …

The endometrium is a complex tissue that lines the inside of the endometrial cavity. The
gene expression of the different endometrial cell types is regulated by ovarian steroids and …

The human endometrium undergoes cyclic remodeling and differentiation to provide an
optimal environment for embryo implantation and development. Endometrial receptivity, the …

STUDY QUESTION Do genetic effects regulate gene expression in human endometrium?
SUMMARY ANSWER This study demonstrated strong genetic effects on endometrial gene …

Endometriosis is a debilitating gynecological disorder affecting approximately 10% of the
female population. Despite its prevalence, robust methods to classify and treat …

Endometriosis is a heritable, complex chronic inflammatory disease, for which much of the
causal pathogenic mechanism remains unknown. Genome-wide association studies …

STUDY QUESTION Do women with endometriosis have a different endometrial gene
expression profile at the time of embryo implantation than women without endometriosis …

Transcriptomic approaches are increasingly used in reproductive medicine to identify
candidate endometrial biomarkers. However, it is known that endometrial progression in the …

The endometrium is a dynamic tissue that undergoes coordinated changes under the
influence of steroid hormones. This results in proliferation and differentiation culminating in a …