The substituted chloroisoquinolinediones and pyrido [3, 4-b] phenazinediones were
synthesized, and the cytotoxic activity and topoisomerase II inhibitory activity of the prepared …

To investigate the structure–activity relationships of 3-arylisoquinolines, diverse substituted
3-aryisoquinolinamines were synthesized and tested in vitro antitumor activity against four …

A new series of 2, 4-diphenyl-6-aryl pyridines containing hydroxyl group (s) at the ortho,
meta, or para position of the phenyl ring were synthesized, and evaluated for topoisomerase …

A series of new indolizinoquinoxaline-5, 12-dione derivatives were designed and
synthesized via a heterocyclization reaction of 6, 7-dichloroquinoxaline-5, 8-dione with …

A series of 6-arylamino-7-chloro-quinazoline-5, 8-diones were prepared and evaluated for
their in vitro cytotoxicity in cultured human cancer cell lines A549 (lung cancer), Col2 (colon …

Designed and synthesized were a series of pyridines substituted at 2, 4, and 6 positions with
various 5-or 6-memberd heteroaromatics as antitumor agents. They were evaluated their …

A series of indolizinoquinoline-5, 12-dione derivatives (IQDs) are synthesized and evaluated
for their cytotoxic activities toward human lung adenocarcinoma (GLC-82), large-cell lung …

We have designed and synthesized a series of 2, 4, 6-triaryl pyridine derivatives containing
chlorophenyl and phenolic moeity at 2-and 4-position of the central pyridine, respectively …

A new series of thirty-six dihydroxylated 2, 6-diphenyl-4-aryl pyridines containing hydroxyl
groups at the ortho, meta, or para position of 2-and 6-phenyl rings attached to the central …

Twelve dihydroxylated 2, 4, 6-triphenyl pyridines were designed and synthesized which
contain hydroxyl groups at ortho, meta or para position of 2-and 6-phenyl, or 2-and 4-phenyl …