The impact of adjuvant chemotherapy timing on overall survival following colorectal cancer resection

S Nachiappan, A Askari, R Mamidanna… - European Journal of …, 2015 - Elsevier
Background Several studies including two meta-analyses have showed that delay between
surgery and adjuvant chemotherapy adversely impacts colorectal cancer survival. This study …

Factors affecting use and delay (≥ 8 weeks) of adjuvant chemotherapy after colorectal cancer surgery and the impact of chemotherapy-use and delay on oncologic …

IY Kim, BR Kim, YW Kim - PloS one, 2015 - journals.plos.org
Purpose To evaluate factors affecting the use and delay≥ 8 weeks of adjuvant
chemotherapy and the impact of chemotherapy use and delay on survival. Methods …

Initiation of adjuvant chemotherapy within 8 weeks of elective colorectal resection improves overall survival regardless of reoperation

S Nachiappan, A Askari, R Mamidanna… - Colorectal …, 2016 - Wiley Online Library
Aim Reoperation after elective colorectal resection may delay the start of adjuvant
chemotherapy (AC). The study investigated the dual impact of a reoperation and AC delay …

Determining the optimal timing for initiation of adjuvant chemotherapy after resection for stage II and III colon cancer

Z Sun, MA Adam, J Kim, DP Nussbaum… - Diseases of the Colon …, 2016 - journals.lww.com
BACKGROUND: Several reports suggest that the efficacy of adjuvant chemotherapy on
survival diminishes over time for colon cancer; however, precise timing of its loss of benefit …

Does delaying adjuvant chemotherapy after curative surgery for colorectal cancer impair survival? A meta-analysis

G Des Guetz, P Nicolas, GY Perret, JF Morere… - European journal of …, 2010 - Elsevier
BACKGROUND: In stage III colorectal cancer (CRC), adjuvant chemotherapy (CT) is usually
prescribed within two months after curative surgery. Whether or not delaying initiation of CT …

Timing of adjuvant chemotherapy in colorectal cancer

LV Dos Santos, TMV Faria, ABC Lima… - Colorectal …, 2016 - Wiley Online Library
Aim Delay in commencing adjuvant therapy for colorectal cancer seems to impair survival in
some retrospective studies. This study was planned to evaluate its impact on survival …

Association between time to initiation of adjuvant chemotherapy and survival in colorectal cancer: a systematic review and meta-analysis

JJ Biagi, MJ Raphael, WJ Mackillop, W Kong, WD King… - Jama, 2011 - jamanetwork.com
Context Adjuvant chemotherapy (AC) improves survival among patients with resected
colorectal cancer. However, the optimal timing from surgery to initiation of AC is unknown …

Timing of adjuvant and neoadjuvant therapy in colorectal cancers

S Bayraktar, UD Bayraktar, CM Rocha-Lima - Clinical colorectal cancer, 2010 - Elsevier
Surgery remains the only curative therapy for colorectal cancer (CRC); however, several
studies have proved that adjuvant chemotherapy improves the curative rate. A growing body …

The optimal time of starting adjuvant chemotherapy after curative surgery in patients with colorectal cancer

Y Yang, Y Lu, H Tan, M Bai, X Wang, S Ge, T Ning… - BMC cancer, 2023 - Springer
Background Postoperative adjuvant chemotherapy (AC) is now well-accepted as standard
for high-risk stage II and stage III colorectal cancer (CRC) patients, however the optimal time …

Variation in delayed time to adjuvant chemotherapy and disease-specific survival in stage III colon cancer patients

AZ Becerra, CT Aquina, SG Mohile, MA Tejani… - Annals of surgical …, 2017 - Springer
Background There is a paucity of literature quantifying the extent to which time to adjuvant
chemotherapy for stage III colon cancer patients varies between individual surgeons …