Defective Circulating CD4+CD25+Foxp3+CD127low Regulatory T-cells in Patients with Chronic Heart Failure
TT Tang, YJ Ding, YH Liao, X Yu, H Xiao… - Cellular Physiology and …, 2010 - karger.com
Aims: Increasing evidences confirm the role of immune activation in the pathogenesis of
chronic heart failure (CHF). Regulatory T cells appear central to the control of immune …
chronic heart failure (CHF). Regulatory T cells appear central to the control of immune …
Uncontrolled immune response in acute myocardial infarction: unraveling the thread
V Bodi, J Sanchis, J Nunez, L Mainar, G Minana… - American heart …, 2008 - Elsevier
Recently, the theory that hyperinflammation is the body's primary response to potent
stimulus has been challenged. Indeed, a deregulation of the immune system could be the …
stimulus has been challenged. Indeed, a deregulation of the immune system could be the …
Antigen presentation by cardiac fibroblasts promotes cardiac dysfunction
Heart failure (HF) is a leading cause of morbidity and mortality. Studies in animal models
and individuals with HF revealed a prominent role for CD4+ T cell immune responses in the …
and individuals with HF revealed a prominent role for CD4+ T cell immune responses in the …
Contributions of cardiomyocyte–cardiac fibroblast–immune cell interactions in heart failure development
K Fujiu, R Nagai - Basic research in cardiology, 2013 - Springer
The heart contains various types of cells, including cardiomyocytes, cardiac fibroblasts,
many kinds of immune cells and vascular cells. Initial studies mainly focused on …
many kinds of immune cells and vascular cells. Initial studies mainly focused on …
Enhanced expression of inflammatory cytokines and activation markers in T-cells from patients with chronic heart failure
A Yndestad, AM Holm, F Müller… - Cardiovascular …, 2003 - academic.oup.com
Objective: Increasing evidence supports a role for inflammation in chronic heart failure
(CHF). However, the source and the mechanism for this immune activation are unknown. To …
(CHF). However, the source and the mechanism for this immune activation are unknown. To …
Role of innate and adaptive immune mechanisms in cardiac injury and repair
Despite the advances that have been made in developing new therapeutics, cardiovascular
disease remains the leading cause of worldwide mortality. Therefore, understanding the …
disease remains the leading cause of worldwide mortality. Therefore, understanding the …
Monocytes in heart failure: relationship to a deteriorating immune overreaction or a desperate attempt for tissue repair?
S Apostolakis, GYH Lip, E Shantsila - Cardiovascular research, 2010 - academic.oup.com
Monocytes play an important role in immune defence, inflammation, and tissue remodelling.
Nevertheless, the role of monocytes in cardiovascular disease is obscure. Indeed …
Nevertheless, the role of monocytes in cardiovascular disease is obscure. Indeed …
Role of the immune system in cardiac tissue damage and repair following myocardial infarction
Introduction The immune system plays a crucial role in the initiation, development, and
resolution of inflammation following myocardial infarction (MI). The lack of oxygen and …
resolution of inflammation following myocardial infarction (MI). The lack of oxygen and …
[HTML][HTML] Regulatory T cells in chronic heart failure
Y Lu, N Xia, X Cheng - Frontiers in Immunology, 2021 - frontiersin.org
Heart failure is a global problem with high hospitalization and mortality rates. Inflammation
and immune dysfunction are involved in this disease. Owing to their unique function …
and immune dysfunction are involved in this disease. Owing to their unique function …
Cardiac monocytes and macrophages after myocardial infarction
C Peet, A Ivetic, DI Bromage… - Cardiovascular research, 2020 - academic.oup.com
Improvements in early interventions after acute myocardial infarction (AMI), notably, the
increased use of timely reperfusion therapy, have increased survival dramatically in recent …
increased use of timely reperfusion therapy, have increased survival dramatically in recent …