Whom to biopsy: prediagnostic risk stratification with biomarkers, nomograms, and risk calculators
Historically, prostate biopsy was performed because of a prostate-specific antigen (PSA)
level exceeding a specific threshold or suspicious findings on digital rectal examination …
level exceeding a specific threshold or suspicious findings on digital rectal examination …
Defining prostate cancer risk before prostate biopsy
RP Pal, NU Maitra, JK Mellon, MA Khan - Urologic Oncology: Seminars and …, 2013 - Elsevier
Prostate cancer is the most commonly diagnosed cancer in men. At present, patients are
selected for prostate biopsy on the basis of age, serum prostate specific antigen (PSA), and …
selected for prostate biopsy on the basis of age, serum prostate specific antigen (PSA), and …
The role of biomarkers in the assessment of prostate cancer risk prior to prostate biopsy: Which markers matter and how should they be used?
M Schmid, QD Trinh, M Graefen, M Fisch… - World journal of …, 2014 - Springer
Prostate cancer (PCa) screening has been substantially influenced by the clinical
implementation of serum prostate-specific antigen (PSA). In this context, improvement of …
implementation of serum prostate-specific antigen (PSA). In this context, improvement of …
Biomarkers for prostate biopsy and risk stratification of patients with newly diagnosed prostate cancer
S Loeb - Urology practice, 2017 - Elsevier
Introduction Many new markers are now available as an aid for decisions about prostate
biopsy for men without prostate cancer and/or to improve risk stratification for men with …
biopsy for men without prostate cancer and/or to improve risk stratification for men with …
Predicting the outcome of prostate biopsy: comparison of a novel logistic regression‐based model, the prostate cancer risk calculator, and prostate‐specific antigen …
DJ Hernandez, M Han, EB Humphreys… - BJU …, 2009 - Wiley Online Library
OBJECTIVES To develop a logistic regression‐based model to predict prostate cancer
biopsy at, and compare its performance to the risk calculator developed by the Prostate …
biopsy at, and compare its performance to the risk calculator developed by the Prostate …
Incorporating biomarkers into the primary prostate biopsy setting: a cost-effectiveness analysis
Purpose: We performed a cost-effectiveness analysis using the PHI (Prostate Health Index),
4Kscore®, SelectMDx™ and the EPI (ExoDx™ Prostate [IntelliScore]) in men with elevated …
4Kscore®, SelectMDx™ and the EPI (ExoDx™ Prostate [IntelliScore]) in men with elevated …
[HTML][HTML] Predicting prostate biopsy results using a panel of plasma and urine biomarkers combined in a scoring system
M Albitar, W Ma, L Lund, F Albitar, K Diep… - Journal of …, 2016 - ncbi.nlm.nih.gov
Background: Determining the need for prostate biopsy is frequently difficult and more
objective criteria are needed to predict the presence of high grade prostate cancer (PCa). To …
objective criteria are needed to predict the presence of high grade prostate cancer (PCa). To …
Development and validation of a novel multivariate risk score to guide biopsy decision for the diagnosis of clinically significant prostate cancer
Objectives Selecting patients suspected of having prostate cancer (PCa) for a prostate
biopsy remains a challenge. Prostate‐specific antigen (PSA)‐based testing is hampered by …
biopsy remains a challenge. Prostate‐specific antigen (PSA)‐based testing is hampered by …
[HTML][HTML] Risk calculators and updated tools to select and plan a repeat biopsy for prostate cancer detection
Millions of men each year are faced with a clinical suspicion of prostate cancer (PCa) but the
prostate biopsy fails to detect the disease. For the urologists, how to select the appropriate …
prostate biopsy fails to detect the disease. For the urologists, how to select the appropriate …
[HTML][HTML] Biomarkers for detection of clinically significant prostate cancer: contemporary clinical data and future directions
Use of serum prostate-specific antigen (PSA) testing for early detection of prostate cancer
appears to reduce cancer-specific mortality. Due to the limited specificity of PSA for clinically …
appears to reduce cancer-specific mortality. Due to the limited specificity of PSA for clinically …
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