Background: The prominent mitochondrial metabolic changes of the atrium reportedly have
significant impact on electrical signals and structural remodeling which play important roles …

Introduction Atrial fibrillation (AF) is an abnormal heart rhythm characterized by an irregular
beating of the atria and is associated with an increased risk of heart failure, dementia, and …

Atrial fibrillation (AF) is the most prevalent and progressive cardiac arrhythmia worldwide
and is associated with serious complications such as heart failure and ischemic stroke …

Introduction Atrial fibrillation (AF) is the most common, complex, and clinically relevant
arrhythmia [1]. It is a growing medical condition associated with significant morbidity and …

Background The exact mechanism of atrial fibrillation (AF)-induced heart failure (HF)
remains unclear. Proteomics and metabolomics were integrated to in this study, as to …

Background Using human humoral metabolomic profiling, we can discover the diagnostic
biomarkers and pathogenesis of disease. The specific characterization of atrial fibrillation …

Atrial fibrillation (AF) is the most common cardiac arrhythmia affecting approximately 2.2
million Americans. Because several studies have suggested that changes in mitochondrial …

Background Long-chain acyl-carnitines (ACs) are potential arrhythmogenic metabolites.
Their role in atrial fibrillation (AF) remains incompletely understood. Using a systems …

Atrial fibrillation (AF) is an abnormal heart rhythm related to an increased risk of heart failure,
dementia, and stroke. The distinction between valvular and non-valvular AF remains a …

Atrial fibrillation (AF) is a common cardiac arrhythmia, with stroke being its most detrimental
comorbidity. The exact mechanism of AF related stroke (AFS) still needs to be explored. In …