[HTML][HTML] Sustained delivery approaches to improving adaptive immune responses

BS Ou, OM Saouaf, J Baillet, EA Appel - Advanced Drug Delivery Reviews, 2022 - Elsevier
The immune system is one of the most important, complex biological networks regulating
and protecting human health. Its precise modulation can prevent deadly infections and fight …

Micro and nanoparticle‐based delivery systems for vaccine immunotherapy: an immunological and materials perspective

J Leleux, K Roy - Advanced healthcare materials, 2013 - Wiley Online Library
The development and widespread application of vaccines has been one of the most
significant achievements of modern medicine. Vaccines have not only been instrumental in …

Macroscale biomaterials strategies for local immunomodulation

MO Dellacherie, BR Seo, DJ Mooney - Nature Reviews Materials, 2019 - nature.com
The immune system plays key roles in tissue homeostatic and disease processes, and
manipulation of innate and adaptive immune responses is of great promise for a wide array …

Polymeric micro-and nanoparticles for immune modulation

E Ben-Akiva, SE Witte, RA Meyer, KR Rhodes… - Biomaterials …, 2019 - pubs.rsc.org
New advances in biomaterial-based approaches to modulate the immune system are being
applied to treat cancer, infectious diseases, and autoimmunity. Particulate systems are …

[HTML][HTML] Controlling timing and location in vaccines

DJ Irvine, A Aung, M Silva - Advanced Drug Delivery Reviews, 2020 - Elsevier
Vaccines are one of the most powerful technologies supporting public health. The adaptive
immune response induced by immunization arises following appropriate activation and …

[HTML][HTML] Engineering nanoparticles to overcome immunological barriers for enhanced drug delivery

T Malachowski, A Hassel - Engineered Regeneration, 2020 - Elsevier
Nanotechnology has recently gained traction in the medical field as a method of targeted
delivery and timed release of therapeutic drugs. As interest in this field grows, design …

Drug delivery strategies to control macrophages for tissue repair and regeneration

R Garash, A Bajpai… - Experimental biology …, 2016 - journals.sagepub.com
Tissue repair and regeneration is a complex process. Our bodies have an excellent capacity
to regenerate damaged tissues in many situations. However, tissue healing is impaired in …

Stimuli-responsive nanomaterials for therapeutic protein delivery

Y Lu, W Sun, Z Gu - Journal of controlled release, 2014 - Elsevier
Protein therapeutics have emerged as a significant role in treatment of a broad spectrum of
diseases, including cancer, metabolic disorders and autoimmune diseases. The efficacy of …

Biomimetic delivery with micro‐and nanoparticles

SC Balmert, SR Little - Advanced materials, 2012 - Wiley Online Library
The nascent field of biomimetic delivery with micro‐and nanoparticles (MNP) has advanced
considerably in recent years. Drawing inspiration from the ways that cells communicate in …

Combinatorial delivery of immunosuppressive factors to dendritic cells using dual-sized microspheres

JS Lewis, C Roche, Y Zhang, TM Brusko… - Journal of materials …, 2014 - pubs.rsc.org
Microparticulate systems are beginning to show promise for delivery of modulatory agents
for immunotherapeutic applications which modulate dendritic cell (DC) functions. Co …