[HTML][HTML] Biomaterials for nanoparticle vaccine delivery systems
Subunit vaccination benefits from improved safety over attenuated or inactivated vaccines,
but their limited capability to elicit long-lasting, concerted cellular and humoral immune …
but their limited capability to elicit long-lasting, concerted cellular and humoral immune …
Triggered nanoparticles as therapeutics
Drug delivery systems (DDSs) face several challenges including site-specific delivery,
stability, and the programmed release of drugs. Engineered nanoparticle (NP) surfaces with …
stability, and the programmed release of drugs. Engineered nanoparticle (NP) surfaces with …
Macrophage-targeted delivery systems for nucleic acid therapy of inflammatory diseases
Inflammation is an immune response that marks several pathophysiological conditions in
our body. Though adaptive immune cells play a major role in the progression of the disease …
our body. Though adaptive immune cells play a major role in the progression of the disease …
Microneedles for painless transdermal immunotherapeutic applications
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …
the treatment of various diseases. However, owing to the dynamic nature of the immune …
Intradermal delivery for vaccine dose sparing: overview of current issues
D Zehrung, C Jarrahian, A Wales - Vaccine, 2013 - Elsevier
There is a wide range of methods and technologies aimed at improving human vaccine
products and the way they are delivered. Some of these have the potential to increase …
products and the way they are delivered. Some of these have the potential to increase …
Modulation of immune responses using adjuvants to facilitate therapeutic vaccination
V Schijns, A Fernández‐Tejada… - Immunological …, 2020 - Wiley Online Library
Therapeutic vaccination offers great promise as an intervention for a diversity of infectious
and non‐infectious conditions. Given that most chronic health conditions are thought to have …
and non‐infectious conditions. Given that most chronic health conditions are thought to have …
Flexible macromolecule versus rigid particle retention in the injected skin and accumulation in draining lymph nodes are differentially influenced by hydrodynamic size
Therapeutic immunomodulation in the skin, its draining lymph nodes, or both tissues
simultaneously using an intradermal administration scheme is desirable for a variety of …
simultaneously using an intradermal administration scheme is desirable for a variety of …
[HTML][HTML] Hitchhiking on controlled-release drug delivery systems: opportunities and challenges for cancer vaccines
Cancer vaccines represent among the most promising strategies in the battle against
cancers. However, the clinical efficacy of current cancer vaccines is largely limited by the …
cancers. However, the clinical efficacy of current cancer vaccines is largely limited by the …
[HTML][HTML] Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy
BR Burton, GJ Britton, H Fang, J Verhagen… - Nature …, 2014 - nature.com
Antigen-specific immunotherapy combats autoimmunity or allergy by reinstating
immunological tolerance to target antigens without compromising immune function …
immunological tolerance to target antigens without compromising immune function …
Drug nanocarriers to treat autoimmunity and chronic inflammatory diseases
Nanoparticles represent a new generation of drug delivery systems that can be engineered
to harness optimal target selectivity for specific cells and tissues and high drug loading …
to harness optimal target selectivity for specific cells and tissues and high drug loading …