Conspectus Development of vaccine technology that induces long lasting and potent
adaptive immune responses is of vital importance to combat emerging pathogens and to …

Immunotherapy is revolutionizing the treatment of diseases in which dysregulated immune
responses have an important role. However, most of the immunotherapy strategies currently …

Recently, engineering the surface of nanotherapeutics with biologics to provide them with
superior biocompatibility and targeting towards pathological tissues has gained significant …

Polymer microspheres have shown great potential as a next generation adjuvant to replace
or complement existing aluminum salts for vaccine potentiation. Microsphere-based systems …

Adjuvant design has historically had a touch of alchemy at its heart due to its reliance on the
complex biology of innate immune activation. However, a new mechanistic understanding of …

Vaccination using nanocarrier-based delivery systems has recently emerged as a promising
approach for meeting the continued challenge posed by infectious diseases and cancer. A …

Nanoparticle-based drug delivery systems have been synthesized from a wide array of
materials. The therapeutic success of these platforms hinges upon their ability to favorably …

Subunit vaccines offer a safer alternative to traditional organism-based vaccines, but their
immunogenicity is impaired. This hurdle might be overcome by the use of micro-and …

By targeting dendritic cells, polymeric carriers in the nano to lower micron range constitute
very interesting tools for antigen delivery. In this critical review, we review how new …

The introduction of a synthetic material into the body always affects different body systems,
including the defense system. Synthetic polymers are usually thymus-independent antigens …