Alternative methods of vaccine delivery: an overview of edible and intradermal vaccines
E Criscuolo, V Caputo, RA Diotti… - Journal of …, 2019 - Wiley Online Library
Vaccines are recognized worldwide as one of the most important tools for combating
infectious diseases. Despite the tremendous value conferred by currently available vaccines …
infectious diseases. Despite the tremendous value conferred by currently available vaccines …
Crossing the barrier: Targeting epithelial receptors for enhanced oral vaccine delivery
B Devriendt, BG De Geest, BM Goddeeris… - Journal of controlled …, 2012 - Elsevier
Vaccination is the most efficient way to combat and prevent infectious diseases. However,
most vaccines are administered systemically and are ineffective in eliciting protective …
most vaccines are administered systemically and are ineffective in eliciting protective …
Intradermal delivery of vaccine nanoparticles using hollow microneedle array generates enhanced and balanced immune response
L Niu, LY Chu, SA Burton, KJ Hansen… - Journal of controlled …, 2019 - Elsevier
Hollow microneedles can help overcome the skin permeation barrier imposed by the stratum
corneum and facilitate transcutaneous delivery of nanoparticle delivery systems. In the …
corneum and facilitate transcutaneous delivery of nanoparticle delivery systems. In the …
Microparticle-based technologies for vaccines
DT O'Hagan, M Singh, JB Ulmer - Methods, 2006 - Elsevier
Microparticles have been effectively used for many years as delivery systems for drugs and
therapeutic proteins. Their application to the delivery of vaccines is not as extensive, but is …
therapeutic proteins. Their application to the delivery of vaccines is not as extensive, but is …
Designing polymeric particles for antigen delivery
S De Koker, BN Lambrecht, MA Willart… - Chemical Society …, 2011 - pubs.rsc.org
By targeting dendritic cells, polymeric carriers in the nano to lower micron range constitute
very interesting tools for antigen delivery. In this critical review, we review how new …
very interesting tools for antigen delivery. In this critical review, we review how new …
Macrophage cell membrane‐cloaked nanoplatforms for biomedical applications
J Lopes, D Lopes, M Pereira‐Silva, D Peixoto… - Small …, 2022 - Wiley Online Library
Biomimetic approaches utilize natural cell membrane‐derived nanovesicles to camouflage
nanoparticles to circumvent some limitations of nanoscale materials. This emergent cell …
nanoparticles to circumvent some limitations of nanoscale materials. This emergent cell …
Immunomodulating activities of soluble synthetic polymer-bound drugs
B Řı́hová - Advanced drug delivery reviews, 2002 - Elsevier
The introduction of a synthetic material into the body always affects different body systems,
including the defense system. Synthetic polymers are usually thymus-independent antigens …
including the defense system. Synthetic polymers are usually thymus-independent antigens …
Single-injecting, bioinspired nanocomposite hydrogel that can recruit host immune cells in situ to elicit potent and long-lasting humoral immune responses
C Korupalli, WY Pan, CY Yeh, PM Chen, FL Mi… - Biomaterials, 2019 - Elsevier
Vaccination is an effective medical intervention for preventing disease. However, without an
adjuvant, most subunit vaccines are poorly immunogenic. This work develops a bioinspired …
adjuvant, most subunit vaccines are poorly immunogenic. This work develops a bioinspired …
Controlled delivery of peptides and proteins
I Tuncer Degim, N Celebi - Current pharmaceutical design, 2007 - ingentaconnect.com
The final aim/target of Pharmaceutical Sciences is to design successful dosage forms for
effective therapy, considering individual patient needs and compliance. Development of new …
effective therapy, considering individual patient needs and compliance. Development of new …
Nanoparticle-based drug delivery systems for induction of tolerance and treatment of autoimmune diseases
H Li, YG Yang, T Sun - Frontiers in bioengineering and biotechnology, 2022 - frontiersin.org
Autoimmune disease is a chronic inflammatory disease caused by disorders of immune
regulation. Antigen-specific immunotherapy has the potential to inhibit the autoreactivity of …
regulation. Antigen-specific immunotherapy has the potential to inhibit the autoreactivity of …