The monitoring of tissue oxygenation by the technique of near infrared spectroscopy (NIRS)
was first described by Jöbsis in 1977 (Jöbsis, 1977). The technique relies upon the relative …

The use of optical spectroscopy for the non-invasive monitoring of tissue oxygenation and
metabolism is well established (Chance et al., 1975). Historically because of the high …

Abstract Near Infrared Spectroscopy (NIRS) is an optical technique that measures tissue
absorbance of light at several wavelengths in the 700-1000 nm spectral region. From the …

In the brain of the adult rat, the ratio of the absorption coefficient of hemoglobin to that of the
cytochromes is approximately ten and in the newborn rat brain the ratio is even higher …

Near-ir (NIR) spectroscopy (NIRS) is a technique that can probe the brain non-invasively. It
utilizes the fact that within the wavelength region 650-1000 nm there is relatively little …

Non invasive infrared spectroscopy is a well established technique for monitoring changes
in the oxygenation status of tissues (1). The technique has in particular been successfully …

Near-infrared (IR) light easily penetrates biological tissue, and the information offered by in
vivo spectroscopy of cerebral oxygenation is detailed and comes with a high temporal …

In order to quantify near-infrared spectroscopic (NIRS) data on an inhomogeneous medium,
knowledge of the contribution of the various parts of the medium to the total NIRS signal is …

The relative transparency of tissues to near infrared light means that it is possible to
transilluminate intact organs. In the infrared region, oxygen dependent absorptions due to …

Our understanding of human brain function can clearly benefit from neurophysiological
techniques capable of providing dynamic maps of activity. A series of studies is reviewed …