RNA export from the nucleus is thought to be linked to proper processing and packaging into
ribonucleoprotein protein complexes. A system to observe mRNA nuclear export in living …

A hallmark of eukaryotic cells is their separation into compartments. These compartments
are surrounded by membranes that are impermeable to macromolecules. As most proteins …

To enter the nucleus, a protein must transit through one of the largest and most complex
gateways in the eukary-otic cell, the nuclear pore. Consisting of perhaps 1000 proteins (60 …

The evolution of the nucleus imposed on eukaryotic cells the necessity to strictly control
exchange of molecules between the nucleus and the remainder of the cell, not only to …

In eukaryotes, the separation of translation from transcription by the nuclear envelope
enables mRNA modifications such as capping, splicing, and polyadenylation. These …

A defining feature of eukaryotic cells is the presence of a nuclear envelope separating
transcription and DNA replication in the nucleus from the site of protein synthesis in the …

Macromolecules enter or leave the nucleus by using nuclear localization signals (NLS), or
nuclear export signals (NES), respectively. Different types of NLS and NES are recognized …

The compartmentalization of proteins within the nucleus or cytoplasm of a eukaryotic cell
offers opportunity for regulation of cell cycle progression and signalling pathways. Nuclear …

Nuclear protein transport has been the subject of considerable attexition as of late. In part,
this is due to the desire of researchers to contribute towards our knowledge of how proteins …

The past year has seen the publication of a number of papers describing the identification of
cytosolic factors involved in import of proteins to the nucleus. Although, at first glance, this …