mRNAs are transported from the nucleus to the cytoplasm by a machinery conserved from
yeast to humans. Previous studies showed that mRNA export factors are loaded on nascent …

Over the past decade, various studies have indicated that most of the eukaryotic genome is
transcribed at some level. The pervasiveness of transcription might seem surprising when …

In eukaryotic cells, most mRNAs are exported from the nucleus by the transcription export
(TREX) complex, which is loaded onto mRNAs after their splicing and capping. We have …

We have purified a cytosolic protein from Xenopus eggs that is essential for selective protein
import into the cell nucleus. The purified protein, named importin, promotes signal …

Export of mRNA from the nucleus to the cytoplasm is a critical process for all eukaryotic gene
expression. As mRNA is synthesized, it is packaged with a myriad of RNA‐binding proteins …

Messenger RNA export from the nucleus to the cytoplasm plays an essential role in linking
transcription to translation and consequently regulation of protein expression. mRNA export …

Transport of proteins into and out of the nucleus occurs through nuclear pore complexes
(NPCs) and is mediated by the interaction of transport factors with nucleoporins at the NPC …

Nuclear localization signals (NLS) are generally short peptides that act as a signal fragment
that mediates the transport of proteins from the cytoplasm into the nucleus. This NLS …

Heterogeneous nuclear ribonucleoprotein (hnRNP) A1 is an abundant nuclear protein that
plays an important role in pre-mRNA processing and mRNA export from the nucleus. A1 …

In eukaryotic cells, there is continuous exchange of macromolecules between the
nucleoplasm and the cytoplasm. Transport in both directions occurs through nuclear pore …