[HTML][HTML] Apigetrin-enriched Pulmeria alba extract prevents assault of STZ on pancreatic β-cells and neuronal oxidative stress with concomitant attenuation of tissue …

T Abdulrasheed-Adeleke, B Lawal, EI Agwupuye… - Biomedicine & …, 2023 - Elsevier
In the present study, in vitro, in vivo, and in silico models were used to evaluate the
therapeutic potential of Pulmeria alba methanolic (PAm) extract, and we identified the major …

Puerarin protects hippocampal neurons against cell death in pilocarpine-induced seizures through antioxidant and anti-apoptotic mechanisms

N Xie, C Wang, Y Lian, C Wu, H Zhang… - Cellular and molecular …, 2014 - Springer
Puerarin extracted from Radix puerariae has been shown to exert neuroprotective effects.
However, it is still not known whether puerarin protects hippocampal neurons against cell …

Botanical Drug Puerarin Ameliorates Liposaccharide‐Induced Depressive Behaviors in Mice via Inhibiting RagA/mTOR/p70S6K Pathways

J Zhao, Y Jia, W Zhao, H Chen, X Zhang… - Oxidative Medicine …, 2021 - Wiley Online Library
Background. The depressive symptom hallmarks the progression of the neurodegenerative
diseases, especially Alzheimer's disease. Bacterial infection is related to inflammation and …

Inhibition of the TLR/NF‐κB Signaling Pathway and Improvement of Autophagy Mediates Neuroprotective Effects of Plumbagin in Parkinson's Disease

Y Su, M Li, Q Wang, X Xu, P Qin… - Oxidative Medicine …, 2022 - Wiley Online Library
A naphthoquinone molecule known as plumbagin (PL), which has a wide range of
pharmacological properties including antitumor, antioxidation, anti‐inflammation, and …

A critical review on anticancer mechanisms of natural flavonoid puerarin

M Murahari, V Singh, P Chaubey… - Anti-Cancer Agents in …, 2020 - ingentaconnect.com
Cancer is one of the prominent global causes of death and the foremost worldwide health
concern. Despite unprecedented progress in cancer chemoprevention, a vast number of …

Myricetin improves apoptosis after ischemic stroke via inhibiting MAPK-ERK pathway

L Zhang, T Zhou, Q Ji, L He, Y Lan, L Ding, L Li… - Molecular Biology …, 2023 - Springer
Background Neuronal apoptosis is the main cause for the disabilities and deaths of patients
suffered with stroke. Neuroprotectants are clinically used to reduce neuronal apoptosis in …

Miltirone Attenuates Reactive Oxygen Species-Dependent Neuronal Apoptosis in MPP+-Induced Cell Model of Parkinson's Disease Through Regulating the PI3K/Akt …

H Feng, F Xi - Neurochemical Research, 2022 - Springer
Miltirone is a phenanthrene-quinone derived from Salvia miltiorrhiza Bunge with anti-
inflammatory and anti-oxidant effects. Our study aimed to explore the protective effect of …

[HTML][HTML] Eriodictyol Attenuates MCAO-Induced Brain Injury and Neurological Deficits via Reversing the Autophagy Dysfunction

C Wang, Z Ma, Z Wang, S Ming, Y Ding… - Frontiers in Systems …, 2021 - frontiersin.org
The present study was designed to investigate the protective effect of eriodictyol on MCAO-
induced brain injury and its regulation of neural function and to explore the mechanism of its …

Puerarin protects dopaminergic neurons against 6-hydroxydopamine neurotoxicity via inhibiting apoptosis and upregulating glial cell line-derived neurotrophic factor …

G Zhu, X Wang, Y Chen, S Yang, H Cheng… - Planta …, 2010 - thieme-connect.com
Neurodegeneration is one of the primary etiologies in the onset of Parkinson's disease. In
the quest for a new antiparkinsonism treatment the potential benefits of puerarin from the …

Puerarin protects brain tissue against cerebral ischemia/reperfusion injury by inhibiting the inflammatory response

F Zhou, L Wang, P Liu, W Hu, X Zhu… - Neural Regeneration …, 2014 - journals.lww.com
Puerarin, a traditional Chinese medicine, exerts a powerful neuroprotective effect in cerebral
ischemia/reperfusion injury, but its mechanism is unknown. Here, we established rat models …