In bacteria–host interactions, competition for iron is critical for the outcome of the infection.
As a result of its redox properties, this metal is essential for the growth and proliferation of …

FtnA is the major iron‐storage protein of Escherichia coli accounting for≤ 50% of total
cellular iron. The FtnA gene (ftnA) is induced by iron in an Fe2+–Fur‐dependent fashion …

In many bacteria, iron homeostasis is controlled primarily by the ferric uptake regulator (Fur),
a transcriptional repressor. However, some genes, including those involved in iron storage …

Under oxic conditions and at pH 7, ferric iron is insoluble, and complex formation of Fe3+
with ligands is required to supply cells with iron. Bacteria and fungi synthesize and secrete …

Iron is an essential nutrient for most bacteria. Depending on the oxygen available in the
surrounding environment, iron is found in two distinct forms: ferrous (Fe II) or ferric (Fe III) …

Bacteria commonly utilise a unique type of transporter, called Feo, to specifically acquire the
ferrous (Fe 2+) form of iron from their environment. Enterobacterial Feo systems are …

Obtaining and maintaining proper levels of iron are major challenges for most organisms
(reviews may be found in references 2, 9, and 10). The redox features that make iron such a …

Siderophores are essential factors for iron (Fe) acquisition in bacteria during colonization
and infection of eukaryotic hosts, which restrain iron access through iron-binding protein …

Iron is a transition metal utilized by nearly all forms of life for essential cellular processes,
such as DNA synthesis and cellular respiration. During infection by bacterial pathogens, the …

Highlights•HmuUV is the first structure of a heme uptake inner membrane ABC
transporter.•A novel assay was developed to assess in vitro heme uptake for …