Tight regulation of the expression of mRNAs encoding iron uptake proteins is essential to
control iron homeostasis and avoid intracellular iron toxicity. We show that many mRNAs …

Mechanisms to regulate iron homeostasis are very likely billions of years older than those for
oxygen homeostasis since contemporary microbes regulate iron in the absence of oxygen …

Iron is an essential element for the survival and pathogenesis of bacteria. The strict control of
iron homeostasis is mediated by the FUR repressor, which is highly conserved among …

Expression of the iron transport genes, fatB and fatA, in the bacterium Vibrio anguillarum
775 is negatively regulated by the iron concentration in the medium. Here, we show that iron …

The acquisition of iron is essential to establishing virulence among most pathogens. Under
acidic and/or anaerobic conditions, most bacteria utilize the widely distributed ferrous iron …

The ferric uptake regulator (Fur) is a global transcription factor that regulates intracellular
iron homeostasis in bacteria. The current hypothesis states that when the intracellular" free" …

The ferric uptake regulator (Fur) plays a major role in controlling the expression of iron
homeostasis genes in bacterial organisms. In this work, we fully characterized the capacity …

The use of iron as a cofactor in basic metabolic pathways is essential to both pathogenic
microorganisms and their hosts. It is also a pivotal component of the innate immune …

Iron is an essential element for the growth and development of all the scale of living
organisms, and acquiring iron is crucial for the development of any pathogen. Iron …