Antibacterial and antifungal activities of isoquinoline alkaloids of the Papaveraceae and Fumariaceae families and their implications in structure–activity relationships

FG Avci, B Atas, GG Toplan, C Gurer… - Studies in Natural …, 2021 - Elsevier
Historically, plants with a wide range of natural products they possess have long served as
important sources of therapeutical agents. Unfortunately, progress in the construction of …

[HTML][HTML] Naturally-occurring alkaloids of plant origin as potential antimicrobials against antibiotic-resistant infections

B Casciaro, L Mangiardi, F Cappiello, I Romeo… - Molecules, 2020 - mdpi.com
Antibiotic resistance is now considered a worldwide problem that puts public health at risk.
The onset of bacterial strains resistant to conventional antibiotics and the scarcity of new …

[HTML][HTML] Research progress on antibacterial activities and mechanisms of natural alkaloids: A review

Y Yan, X Li, C Zhang, L Lv, B Gao, M Li - Antibiotics, 2021 - mdpi.com
Alkaloids are nitrogen-containing heterocyclic compounds typically isolated from plants.
They represent one of the most important types of natural products because of their large …

Alkaloids: An overview of their antibacterial, antibiotic-enhancing and antivirulence activities

TPT Cushnie, B Cushnie, AJ Lamb - International journal of antimicrobial …, 2014 - Elsevier
With reports of pandrug-resistant bacteria causing untreatable infections, the need for new
antibacterial therapies is more pressing than ever. Alkaloids are a large and structurally …

Antifungal potential of alkaloids as an emerging therapeutic target

H Khan, MS Mubarak, S Amin - Current drug targets, 2017 - ingentaconnect.com
Background: Fungal infections have been causing serious problems in all age groups,
especially in immune-compromised individuals. Various synthetic agents are in clinical …

Antiviral and antimicrobial profiles of selected isoquinoline alkaloids from Fumaria and Corydalis species

I Orhan, B Özçelik, T Karaoğlu… - … für Naturforschung C, 2007 - degruyter.com
In the current study, 33 isoquinoline alkaloids belonging to protopine-, benzylisoquinoline-,
benzophenanthridine-, spirobenzylisoquinoline-, phthalideisoquinoline-, aporphine …

Ethnobotany and the role of plant natural products in antibiotic drug discovery

G Porras, F Chassagne, JT Lyles, L Marquez… - Chemical …, 2020 - ACS Publications
The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …

Alkaloids with antiprotozoal activity

EJ Osorio, SM Robledo, J Bastida - The Alkaloids: Chemistry and Biology, 2008 - Elsevier
Publisher Summary This chapter discusses the alkaloid natural products that are particularly
active against Leishmania sp., Trypanosomacruzi, Trypanosomabrucei, and Plasmodium …

Antibacterial constituents of the plant family Amaryllidaceae

JJ Nair, A Wilhelm, SL Bonnet, J van Staden - Bioorganic & medicinal …, 2017 - Elsevier
There is a pressing need in antibiotic drug discovery for new drugs to counterbalance the
effects of multidrug resistance. Plants represent a viable platform for such endeavors owing …

Plant natural products as a potential source for antibacterial agents: recent trends

M Shahid, A Shahzad, F Sobia, A Sahai… - Anti-Infective Agents …, 2009 - ingentaconnect.com
Pasteur and Joubert, in 1877, were among the first to recognize the potential of microbial
products as therapeutic agents and demonstrated that common microorganisms could …