Antifungal discovery from plant sources
JS Prusty - Phytoconstituents and Antifungals, 2022 - Elsevier
Plants produce potent constitutive and induced antifungal compounds to complement the
structural barriers to microbial infection. A wide spectrum of compound classes has been …
structural barriers to microbial infection. A wide spectrum of compound classes has been …
Alkaloids from the tribe Bocconieae (Papaveraceae): A chemical and biological review
X Yu, X Gao, Z Zhu, Y Cao, Q Zhang, P Tu, X Chai - Molecules, 2014 - mdpi.com
The Bocconieae tribe, consisting of only the genera Macleaya and Bocconia, possesses
significant economic and medicinal value and plays an important role in health management …
significant economic and medicinal value and plays an important role in health management …
Asymmetric synthesis and study of biological activity of (epi-) benzoanalogues of bioactive phenanthroquinolizidine alkaloids
T Pagáč, P Šafář, Š Marchalín, Z Ježíková… - Monatshefte für Chemie …, 2018 - Springer
The increasing microbial resistance to primary active structures remains alarming and the
effort to look for new antibacterial active structures is still of scientific interest. One of the …
effort to look for new antibacterial active structures is still of scientific interest. One of the …
Alkaloids from marine fungi: Promising antimicrobials
T Willems, ML De Mol, A De Bruycker… - Antibiotics, 2020 - mdpi.com
Resistance of pathogenic microorganisms against antimicrobials is a major threat to
contemporary human society. It necessitates a perpetual influx of novel antimicrobial …
contemporary human society. It necessitates a perpetual influx of novel antimicrobial …
3-Phenyl-5-methyl-2H, 5H-furan-2-ones: tuning antifungal activity by varying substituents on the phenyl ring
M Pour, M Špulák, V Balšánek, J Kuneš… - Bioorganic & medicinal …, 2000 - Elsevier
A series of racemic 3-phenyl-5-methyl-2H, 5H-furan-2-ones related to a natural product,(−)
incrustoporine, was synthesized, and their antifungal activity evaluated. The key structural …
incrustoporine, was synthesized, and their antifungal activity evaluated. The key structural …
[HTML][HTML] Structural modification may be a way to make isoquinoline alkaloids efficient antibacterial drugs
H Wang, Y Zhao, H Xu, P Wang, S Chen - Arabian Journal of Chemistry, 2023 - Elsevier
Isoquinoline alkaloids are a kind of small molecular compounds with isoquinoline structure
which widely exist in natural plants. A large number of studies have confirmed that these …
which widely exist in natural plants. A large number of studies have confirmed that these …
Therapeutic potential of alkaloids as anti-bacterial agents: drugs of future
Bacterial infections remain a major threat to the world community in terms of both morbidity
and mortality. Indeed, bacterial infections are accountable for millions of fatalities around the …
and mortality. Indeed, bacterial infections are accountable for millions of fatalities around the …
Antifungal activity against Fusarium oxysporum of quinolizidines isolated from three controlled-growth Genisteae plants: structure–activity relationship implications
W Cely-Veloza, L Yamaguchi, D Quiroga… - Natural Products and …, 2023 - Springer
The Genisteae tribe belongs to the Fabaceae family. The wide occurrence of secondary
metabolites, explicitly highlighting the quinolizidine alkaloids (QAs), characterizes this tribe …
metabolites, explicitly highlighting the quinolizidine alkaloids (QAs), characterizes this tribe …
Selected fungal natural products with antimicrobial properties
D Jakubczyk, F Dussart - Molecules, 2020 - mdpi.com
Fungal natural products and their effects have been known to humankind for hundreds of
years. For example, toxic ergot alkaloids produced by filamentous fungi growing on rye …
years. For example, toxic ergot alkaloids produced by filamentous fungi growing on rye …
[HTML][HTML] A plumieridine-rich fraction from Allamanda polyantha inhibits chitinolytic activity and exhibits antifungal properties against Cryptococcus neoformans
E Silva e Souza, VA Barcellos, N Sbaraini… - Frontiers in …, 2020 - frontiersin.org
Cryptococcosis is a fungal infection caused mainly by the pathogenic yeasts Cryptococcus
neoformans and Cryptococcus gattii. The infection initiates with the inhalation of propagules …
neoformans and Cryptococcus gattii. The infection initiates with the inhalation of propagules …