Invasive fungal infections are accompanied by high mortality rates that range up to 90%. At
present, only three different compound classes are available for use in the clinic, and these …

Phenylpropanoids belong to a wide group of compounds commonly secreted by plants and
involved in different roles related with plant growth and development and the defense …

This paper reviewed the antibacterial activity and structure-activity relationship of
isoquinoline alkaloids, such as protoberberine, protopine, benzophenanthridine, aporphine …

Plant flavonoids have attracted increasing attention as new antimicrobial agents or
adjuvants. In our previous work, it was confirmed that the cell membrane is the major site of …

Throughout the ages the world has witnessed the outbreak of many infectious diseases.
Emerging microbial diseases pose a serious threat to public health. Increasing resistance of …

Background: Medicinal plants have been used to treat diseases for centuries. They are
important sources in terms of their pharmacological effects and also have many microbial …

Chelidonium majus (Papaveraceae) extracts exhibit antimicrobial activity due to the complex
alkaloid composition. The aim of the research was to evaluate the antimicrobial potential of …

In the last three decades, invasive fungal infections caused by Candida species have
become an important public health problem, because they are associated with high rates of …

Previous studies on the indoloquinoline alkaloid, cryptolepine (2), revealed that it has antii-
nfective properties among other activities. Using Structure–activity relationship (SAR) …

Among the novel approaches applied to antimicrobial drug development, natural product-
inspired synthesis plays a major role, by providing biologically validated starting points …