Tønnesen P, Tonstad S, Hjalmarson A, Lebargy F, van Spiegel PI, Hider A, Sweet R,
Townsend J (Gentofte University Hospital, Gentofte, Denmark; Clinic for Preventive …

Background Studies undertaken in academic settings have shown that bupropion
hydrochloride can double the odds of smoking cessation compared with placebo. To assess …

Background Bupropion hydrochloride is recommended for smoking cessation; however,
there have been relatively few clinical trials examining its efficacy. Methods A total of 244 …

Objectives: To identify predictors of smoking abstinence at the end of medication use that
could assist in the optimal use of a sustained-release (SR) form of bupropion for treating …

Background Many persons who attempt to quit smoking have made previous unsuccessful
attempts to quit with pharmacologic aids. An understanding of the impact of these previous …

Efficacy of bupropion SR and individual counseling as smoking cessation treatments was
assessed in a randomized, placebo-controlled clinical trial among adult daily smokers …

PURPOSE: To determine whether sustained-release bupropion promotes smoking
reduction leading to smoking cessation among persons who wish to reduce their amount of …

Sustained release bupropion (amfebutamone) is a non-nicotine agent that is indicated as an
aid to smoking cessation. In 2 large well designed clinical trials, sustained release …

Bupropion SR was introduced for smoking cessation in the US in 1997. This review
assesses the efficacy and safety of bupropion SR for treatment of tobacco dependence …

Background Previous published studies assessed the efficacy of bupropion in smoking
cessation only in North American populations of smokers. Results of therapeutic drug trials …