High-fat diet and female fertility

NM Hohos, ME Skaznik-Wikiel - Endocrinology, 2017 - academic.oup.com
The prevalence of obesity is high among reproductive-age women and is associated with
impaired reproductive function. Obesity is multifactorial in origin, yet many cases of obesity …

[HTML][HTML] Obesity and its impact on female reproductive health: Unraveling the connections

L Zheng, L Yang, Z Guo, N Yao, S Zhang… - Frontiers in …, 2024 - frontiersin.org
In the modern era, the escalating global prevalence of obesity has profound implications on
female reproductive health. Obesity, transcending mere lifestyle choices, has evolved into a …

Weighing the impact of obesity on female reproductive function and fertility

ES Jungheim, JL Travieso, MM Hopeman - Nutrition reviews, 2013 - academic.oup.com
Obesity in women is associated with serious reproductive sequelae. Given its prevalence
among women of reproductive age, much recent attention has focused on the mechanisms …

High-fat diet exposure, regardless of induction of obesity, is associated with altered expression of genes critical to normal ovulatory function

NM Hohos, KJ Cho, DC Swindle… - Molecular and Cellular …, 2018 - Elsevier
We evaluated the impact of high-fat diet (HFD) on ovarian gene expression. Female 5-week-
old C57BL/6J mice were fed a 60% HFD or standard chow for 10 weeks. HFD-fed mice were …

Metabolic effects of obesity on reproduction

R Pasquali, A Gambineri - Reproductive biomedicine online, 2006 - Elsevier
Obese women are characterized by similar comorbidities to men, particularly type 2 diabetes
mellitus and cardiovascular diseases. Moreover, they also develop some specific problems …

[HTML][HTML] High-fat diet and female fertility across lifespan: a comparative lesson from mammal models

C Di Berardino, A Peserico, G Capacchietti… - Nutrients, 2022 - mdpi.com
Female reproduction focuses mainly on achieving fully grown follicles and competent
oocytes to be successfully fertilized, as well as on nourishing the developing offspring once …

[HTML][HTML] Obesity and female infertility: potential mediators of obesity's impact

DE Broughton, KH Moley - Fertility and sterility, 2017 - Elsevier
The worldwide upward trend in obesity has been dramatic, now affecting more than 20% of
American women of reproductive age. Obesity is associated with many adverse maternal …

The effect of excess body fat on female and male reproduction

G Mintziori, MP Nigdelis, H Mathew, A Mousiolis… - Metabolism, 2020 - Elsevier
The dramatic increase in the prevalence of obesity coincides with a decline in reproductive
health indices in both sexes. Energy excess mediates changes to the regulatory …

Female infertility: which role for obesity?

A Gambineri, D Laudisio, C Marocco… - International journal of …, 2019 - nature.com
Obesity is associated with infertility in women through multiple and complex mechanisms.
Briefly, the adipose tissue through the production of many factors, such as leptin, free fatty …

High-fat diet causes subfertility and compromised ovarian function independent of obesity in mice

ME Skaznik-Wikiel, DC Swindle… - Biology of …, 2016 - academic.oup.com
Excess calorie consumption, particularly of a diet high in fat, is a risk factor for both obesity
and reproductive disorders. Animal model studies indicate that elevated dietary fat can …