MiR-196: emerging of a new potential therapeutic target and biomarker in colorectal cancer

P Pourdavoud, B Pakzad, M Mosallaei… - Molecular Biology …, 2020 - Springer
Deregulation of microRNAs, as key elements in colorectal cancer (CRC) pathogenesis, is
correlated with various stages of this cancer. miR-196 is involved in the initiation and …

[HTML][HTML] miR-196, an emerging cancer biomarker for digestive tract cancers

YC Lu, JT Chang, EC Chan, YK Chao, TS Yeh… - Journal of …, 2016 - ncbi.nlm.nih.gov
Over the past decade, the emergence of microRNA (miRNA) research has firmly established
this molecular family as a key component in cells. MiRNAs, which function as negative gene …

Expression profiles of miR-196, miR-132, miR-146a, and miR-134 in human colorectal cancer tissues in accordance with their clinical significance: Comparison …

M Maralani, D Shanehbandi, M Asadi… - Wiener klinische …, 2021 - Springer
Background Colorectal cancer (CRC) is among the most widespread malignancies in the
world. MicroRNA (miRNA) has been identified as an important modulator of the biological …

[HTML][HTML] The diagnostic potential of miR-196a-1 in colorectal cancer

B Mehrjoei, L Haghnazari, H Bashiri, N Rezvani - BMC cancer, 2024 - Springer
Background Colorectal cancer (CRC) is a common malignancy worldwide. MicroRNAs
(miRNAs) are important epigenetic alterations that notably impact various physiological and …

[HTML][HTML] Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer

GM Arndt, L Dossey, LM Cullen, A Lai, R Druker… - BMC cancer, 2009 - Springer
Abstract Background MicroRNAs (MiRNAs) are short non-coding RNAs that control protein
expression through various mechanisms. Their altered expression has been shown to be …

[HTML][HTML] Increased expression of miRNA-182 in colorectal carcinoma: an independent and tissue-specific prognostic factor

S Wang, MH Yang, XY Wang, J Lin… - International journal of …, 2014 - ncbi.nlm.nih.gov
Increasing evidence has revealed that miRNAs play a pivotal role in multiple processes of
carcinogenesis, and are being explored as diagnostic, prognostic and predictive biomarker …

MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway

B Wang, Z Shen, Z Gao, G Zhao, C Wang, Y Yang… - Cell cycle, 2015 - Taylor & Francis
Tumor growth cascade is a complicated and multistep process with numerous obstacles.
Until recently, evidences have shown the involvement of microRNAs (miRNAs) in …

[HTML][HTML] The potential value of miR-1 and miR-374b as biomarkers for colorectal cancer

X Wu, S Li, X Xu, S Wu, R Chen, Q Jiang… - International journal of …, 2015 - ncbi.nlm.nih.gov
The mortality of colorectal cancer (CRC) is growing due to the unsatisfactory specificity and
sensitivity of the existing screening methods. Previous studies have focused on the role of …

[HTML][HTML] The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer

M Takahashi, M Cuatrecasas, F Balaguer, K Hur… - 2012 - journals.plos.org
Aim Development of robust prognostic and/or predictive biomarkers in patients with
colorectal cancer (CRC) is imperative for advancing treatment strategies for this disease. We …

[HTML][HTML] Upregulation of microRNA-196a and microRNA-196b cooperatively correlate with aggressive progression and unfavorable prognosis in patients with …

J Ge, Z Chen, R Li, T Lu, G Xiao - Cancer cell international, 2014 - Springer
Abstract Background Both microRNA (miR)-196a and miR-196b are implicated in normal
cell differentiation, proliferation, and in tumorigenesis of various cancer types. Especially …