MiR-196: emerging of a new potential therapeutic target and biomarker in colorectal cancer
P Pourdavoud, B Pakzad, M Mosallaei… - Molecular Biology …, 2020 - Springer
Deregulation of microRNAs, as key elements in colorectal cancer (CRC) pathogenesis, is
correlated with various stages of this cancer. miR-196 is involved in the initiation and …
correlated with various stages of this cancer. miR-196 is involved in the initiation and …
[HTML][HTML] miR-196, an emerging cancer biomarker for digestive tract cancers
YC Lu, JT Chang, EC Chan, YK Chao, TS Yeh… - Journal of …, 2016 - ncbi.nlm.nih.gov
Over the past decade, the emergence of microRNA (miRNA) research has firmly established
this molecular family as a key component in cells. MiRNAs, which function as negative gene …
this molecular family as a key component in cells. MiRNAs, which function as negative gene …
Expression profiles of miR-196, miR-132, miR-146a, and miR-134 in human colorectal cancer tissues in accordance with their clinical significance: Comparison …
M Maralani, D Shanehbandi, M Asadi… - Wiener klinische …, 2021 - Springer
Background Colorectal cancer (CRC) is among the most widespread malignancies in the
world. MicroRNA (miRNA) has been identified as an important modulator of the biological …
world. MicroRNA (miRNA) has been identified as an important modulator of the biological …
[HTML][HTML] The diagnostic potential of miR-196a-1 in colorectal cancer
B Mehrjoei, L Haghnazari, H Bashiri, N Rezvani - BMC cancer, 2024 - Springer
Background Colorectal cancer (CRC) is a common malignancy worldwide. MicroRNAs
(miRNAs) are important epigenetic alterations that notably impact various physiological and …
(miRNAs) are important epigenetic alterations that notably impact various physiological and …
[HTML][HTML] Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer
GM Arndt, L Dossey, LM Cullen, A Lai, R Druker… - BMC cancer, 2009 - Springer
Abstract Background MicroRNAs (MiRNAs) are short non-coding RNAs that control protein
expression through various mechanisms. Their altered expression has been shown to be …
expression through various mechanisms. Their altered expression has been shown to be …
[HTML][HTML] Increased expression of miRNA-182 in colorectal carcinoma: an independent and tissue-specific prognostic factor
S Wang, MH Yang, XY Wang, J Lin… - International journal of …, 2014 - ncbi.nlm.nih.gov
Increasing evidence has revealed that miRNAs play a pivotal role in multiple processes of
carcinogenesis, and are being explored as diagnostic, prognostic and predictive biomarker …
carcinogenesis, and are being explored as diagnostic, prognostic and predictive biomarker …
MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway
B Wang, Z Shen, Z Gao, G Zhao, C Wang, Y Yang… - Cell cycle, 2015 - Taylor & Francis
Tumor growth cascade is a complicated and multistep process with numerous obstacles.
Until recently, evidences have shown the involvement of microRNAs (miRNAs) in …
Until recently, evidences have shown the involvement of microRNAs (miRNAs) in …
[HTML][HTML] The potential value of miR-1 and miR-374b as biomarkers for colorectal cancer
X Wu, S Li, X Xu, S Wu, R Chen, Q Jiang… - International journal of …, 2015 - ncbi.nlm.nih.gov
The mortality of colorectal cancer (CRC) is growing due to the unsatisfactory specificity and
sensitivity of the existing screening methods. Previous studies have focused on the role of …
sensitivity of the existing screening methods. Previous studies have focused on the role of …
[HTML][HTML] The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer
M Takahashi, M Cuatrecasas, F Balaguer, K Hur… - 2012 - journals.plos.org
Aim Development of robust prognostic and/or predictive biomarkers in patients with
colorectal cancer (CRC) is imperative for advancing treatment strategies for this disease. We …
colorectal cancer (CRC) is imperative for advancing treatment strategies for this disease. We …
[HTML][HTML] Upregulation of microRNA-196a and microRNA-196b cooperatively correlate with aggressive progression and unfavorable prognosis in patients with …
J Ge, Z Chen, R Li, T Lu, G Xiao - Cancer cell international, 2014 - Springer
Abstract Background Both microRNA (miR)-196a and miR-196b are implicated in normal
cell differentiation, proliferation, and in tumorigenesis of various cancer types. Especially …
cell differentiation, proliferation, and in tumorigenesis of various cancer types. Especially …
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