Cardiovascular responses to rat/mouse hemokinin-1, a mammalian tachykinin peptide: systemic study in anesthetized rats

CY Fu, ZQ Kong, Y Long, Q Chen, R Wang - European journal of …, 2007 - Elsevier
Rat/mouse hemokinin-1 is a mammalian tachykinin peptide whose biological functions have
not been well characterized. In the present study, an attempt has been made to investigate …

Cardiovascular responses to intravenous administration of human hemokinin-1 and its truncated form hemokinin-1 (4-11) in anesthetized rats

ZQ Kong, CY Fu, Q Chen, R Wang - European journal of pharmacology, 2008 - Elsevier
Human hemokinin-1 and its carboxy-terminal fragment human hemokinin-1 (4-11) have
been recently identified as the members of the tachykinin family. The peripheral …

Effects of rat/mouse hemokinin-1, human hemokinin-1 and human hemokinin-1 (4-11), mammalian tachykinin peptides, on rate and perfusion pressure in the isolated …

ZQ Kong, WL Yang, Y Tao, XM Shi, CY Fu, RF Zhao… - Neuropeptides, 2010 - Elsevier
Rat/mouse hemokinin-1 (r/m HK-1), human hemokinin-1 (h HK-1) and human hemokinin-1
(4-11)(h HK-1 (4-11)) are members of the tachykinin family. In the present study, the …

Mechanisms of relaxing response induced by rat/mouse hemokinin-1 in porcine coronary arteries: roles of potassium ion and nitric oxide

Y Long, CY Fu, XZ Tian, J Chen, M Han… - European journal of …, 2007 - Elsevier
Rat and mouse hemokinin-1 (r/m hemokinin-1) is a recently described member of the
tachykinin family whose cardiovascular functions are not fully understood. In this study, we …

Possible mechanism of the vasodepressor effect of endokinin a/b in anesthetized rats

AM Abdelrahman, H Syyong, A Tjahjadi… - Journal of …, 2005 - journals.lww.com
We investigated the mechanism of the vasodepressor effect of endokinin A/B. An
intravenous (IV) bolus of endokinin A/B (0.05-0.3 nmol/kg) dose-dependently decreased …

Hypotensive effect of intravenous injection of tachykinins in conscious, freely moving spontaneously hypertensive and Wistar Kyoto rats

P Pompei, SJ Tayebati, C Polidori, M Perfumi… - Peptides, 1993 - Elsevier
The present study evaluated the sensitivity of spontaneously hypertensive (SHR) and of
Wistar Kyoto (WKY) rats to the hypotensive effect of tachykinins (TKs). Eledoisin, substance …

FAILURE OF ENDOGENOUS BLOOD KININ LEVELS ELEVATED BY CAPTOPRIL TO INDUCE HYPOTENSION IN NORMOTENSIVE AND HYPERTENSIVE RATS: A …

M MAJIMA, M KATORI, M OGINO, M SAITO… - Biomedical …, 1996 - jstage.jst.go.jp
ABSTRACT Captopril (10 mg/kg, ip) increased the arterial bradykinin (BK) level of non-
treated Sprague-Dawley rats, determined by a newly developed ELISA, from 10.8 i 3.2 pg/ml …

Pharmacological profile of hemokinin 1: a novel member of the tachykinin family

V Camarda, A Rizzi, G Calo, R Guerrini, S Salvadori… - Life sciences, 2002 - Elsevier
Recently, the cloning of a novel preprotachykinin gene (PPT-C) has been reported. This
gene codes for a novel peptide named hemokinin 1 (HK-1). In contrast with the known …

Chronic inhibition of bradykinin B2-receptors enhances the slow vasopressor response to angiotensin II.

P Madeddu, PP Parpaglia, MP Demontis, MV Varoni… - …, 1994 - Am Heart Assoc
The contribution of endogenous kinins in the regulation of blood pressure of angiotensin-
treated rats was evaluated using the new bradykinin B2-receptor antagonist Hoe 140 (D …

Role of central tachykinin peptides in cardiovascular regulation in rats

Y Takano, A Nagashima, T Hagio, K Tateishi, H Kamiya - Brain research, 1990 - Elsevier
The mechanisms of action of tachykinin peptides thought to be involved in central
cardiovascular regulation were examined. Intracerebroventricular injections (icv) of …