Chordoma is a rare malignant axial tumour that develops from embryonic remnants of the
notochord. Surgery and irradiation are the standard initial treatment. However, local …

Background Chordomas are very rare low-grade malignant bone tumors that arise from the
embryonic rests of the notochord. They are characterized by slow growth and long history …

Chordomas are rare tumors arising from the axial skeleton. The disease is characterized by
slow local growth, frequent local recurrences, and rare systemic spread. Surgery and local …

Background Chordoma is a rare, slow growing and locally aggressive mesenchymal
neoplasm with uncommon distant metastases. It is a chemo-resistant disease with surgery …

Chordomas are rare tumors that arise from the vestigial or ectopic notochord, with an
incidence of 0.5 to 0.8 per 1 000 000 [1, 2]. About 50% originate from the sacrococcygeal …

Chordomas are rare primary malignant bone tumors arising from embryonal notochord
remnants of the axial skeleton. Chordomas commonly recur following surgery and …

Background Chordomas are rare malignant tumours of the axial skeleton and skull base
supposed to arise from cellular remnants of the notochord. These tumours have the potential …

Background Chordoma is a rare malignant tumor of the skull base and axial skeleton, with
an incidence of less than 0.1/100,000 per year. Patients with advanced chordoma have a …

Chordoma is a rare tumour arising from the embryonal remnants of a notochord occurring
most commonly in the sacrococcygeal as well as head and neck locations. Current treatment …

Introduction Imatinib showed activity in 50 chordoma patients treated within a Phase II study.
In that study, 70% of patients remained with stable disease (SD), median progression free …