Neuroinflammation during RNA viral infections
Neurotropic RNA viruses continue to emerge and are increasingly linked to diseases of the
central nervous system (CNS) despite viral clearance. Indeed, the overall mortality of viral …
central nervous system (CNS) despite viral clearance. Indeed, the overall mortality of viral …
Viral encephalitis and neurologic diseases: focus on astrocytes
Neurotropic RNA virus infections cause a major neurological disease burden. Due to the
morbidity and mortality rates of viral encephalitides worldwide, there is a need to develop …
morbidity and mortality rates of viral encephalitides worldwide, there is a need to develop …
Orchestration of antiviral responses within the infected central nervous system
A Pavlou, F Mulenge, OL Gern, LM Busker… - Cellular & molecular …, 2024 - nature.com
Many newly emerging and re-emerging viruses have neuroinvasive potential, underscoring
viral encephalitis as a global research priority. Upon entry of the virus into the CNS, severe …
viral encephalitis as a global research priority. Upon entry of the virus into the CNS, severe …
Keeping it in check: chronic viral infection and antiviral immunity in the brain
KD Miller, MJ Schnell, GF Rall - Nature Reviews Neuroscience, 2016 - nature.com
It is becoming clear that the manner by which the immune response resolves or contains
infection by a pathogen varies according to the tissue that is affected. Unlike many …
infection by a pathogen varies according to the tissue that is affected. Unlike many …
Molecular mechanisms associated with neurodegeneration of neurotropic viral infection
P Wongchitrat, T Chanmee, P Govitrapong - Molecular Neurobiology, 2024 - Springer
Viral infections of the central nervous system (CNS) cause variable outcomes from acute to
severe neurological sequelae with increased morbidity and mortality. Viral neuroinvasion …
severe neurological sequelae with increased morbidity and mortality. Viral neuroinvasion …
Immune responses to RNA-virus infections of the CNS
DE Griffin - Nature Reviews Immunology, 2003 - nature.com
A successful outcome for the host of virus infection of the central nervous system (CNS)
requires the elimination of the virus without damage to essential non-renewable cells, such …
requires the elimination of the virus without damage to essential non-renewable cells, such …
Illuminating viral infections in the nervous system
DB McGavern, SS Kang - Nature Reviews Immunology, 2011 - nature.com
Viral infections are a major cause of human disease. Although most viruses replicate in
peripheral tissues, some have developed unique strategies to move into the nervous …
peripheral tissues, some have developed unique strategies to move into the nervous …
Viral CNS infections: role of glial pattern recognition receptors in neuroinflammation
SR Furr, I Marriott - Frontiers in microbiology, 2012 - frontiersin.org
Viruses are the major causative agents of central nervous system (CNS) infection worldwide.
RNA and DNA viruses trigger broad activation of glial cells including microglia and …
RNA and DNA viruses trigger broad activation of glial cells including microglia and …
Neural immunity: Friend or foe?
HE Gendelman - Journal of neurovirology, 2002 - Taylor & Francis
The articles compiled in this special edition of Journal of NeuroVirology target a developing
field of investigation seeking to uncover how the immune system affects both the pathogenic …
field of investigation seeking to uncover how the immune system affects both the pathogenic …
Infectious immunity in the central nervous system and brain function
RS Klein, C Garber, N Howard - Nature immunology, 2017 - nature.com
Inflammation is emerging as a critical mechanism underlying neurological disorders of
various etiologies, yet its role in altering brain function as a consequence of neuroinfectious …
various etiologies, yet its role in altering brain function as a consequence of neuroinfectious …