The presence of intrathecal IgM synthesis (ITMS) has been associated with an aggressive
multiple sclerosis (MS) clinical course. In the present systematic review, we aimed at …

We assessed the frequency of cerebrospinal fluid (CSF) restricted oligoclonal IgG bands
(IgG-OCB) in Portuguese multiple sclerosis (MS) patients and its relationship with outcome …

Objective To determine the best method to measure intrathecal immunoglobulin (Ig) M
synthesis (ITMS), a biomarker of worse prognosis in multiple sclerosis (MS). We compared …

Background: There is emerging evidence that intrathecal IgM synthesis (ITMS) is a risk factor
for conversion to clinically defined multiple sclerosis (CDMS) in clinically isolated syndrome …

The objective of this study was to investigate, whether the presence of oligoclonal
immunoglobulin M bands (IgM‐OCB) in cerebrospinal fluid (CSF) from patients with a …

Lower prevalence of cerebrospinal fluid oligoclonal IgG bands (IgG-OCBs) has been
reported in multiple sclerosis (MS) patients from Southern Europe compared to other …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). Presence of plaques is the main pathological feature of MS …

Background: Multiple sclerosis (MS) is the most common demyelinating disease and
characterized by immunological changes. Oligoclonal bands of IgG in CSF not seen in …

Introduction Intrathecal immunoglobulin G (IgG) and oligoclonal bands (OCBs) are the most
consistent and characteristic features of Multiple Sclerosis (MS). OCBs in MS are considered …

Objectives–To investigate the significance of oligoclonal bands (OCBs) and intrathecal IgG
fractions (IgGIF) for the diagnosis of multiple sclerosis (MS) in northern China. Materials and …